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J Infect Dis ; 167(2): 451-4, 1993 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-8421179

RESUMEN

In April 1991, 91 hospitalized patients in Cairo were reported to the Egyptian Ministry of Health with botulism intoxication. To define the spectrum of illness and identify a food vehicle, 45 patients were interviewed and a case-control investigation was conducted among families of 5 hospitalized patients. Clinical specimens and specimens of implicated food were tested for toxin and cultured for Clostridium botulinum. Hospitalized patients had symptoms consistent with botulism; 18 (20%) of 91 reported patients died. Illness was associated with eating faseikh (uneviscerated, salted mullet fish; lower 95% confidence limit of odds ratio = 6.6, P < .001). All 5 case-families purchased faseikh from one shop. Very high levels of type E botulinal toxin were detected in faseikh reported to be purchased from the implicated shop; C. botulinum type E was isolated from cultures of clinical specimens and from the faseikh. This is the first documented outbreak of botulism in Egypt and the largest type E outbreak ever reported.


Asunto(s)
Botulismo/epidemiología , Brotes de Enfermedades , Productos Pesqueros/envenenamiento , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Animales , Toxinas Botulínicas/análisis , Botulismo/etiología , Niño , Preescolar , Clostridium botulinum/aislamiento & purificación , Egipto/epidemiología , Heces/microbiología , Femenino , Contenido Digestivo/química , Contenido Digestivo/microbiología , Humanos , Entrevistas como Asunto , Masculino , Persona de Mediana Edad , Perciformes
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