RESUMEN
Coumarins administered in early pregnancy can cause malformations. This so-called coumarin embryopathy is characterized by malformations such as those occurring in chondrodysplasia punctata of the Conradi-Hünermann type, i.e. a syndrome which has been known since 1914. A case observed after coumarin administration (Falithrom) in early pregnancy is described with the features considered typical: Hypoplasia of the nasal bridge and stippled calcification of the skeleton, in particular stippled epiphyses of the long bones. According to reports in the literature, the risk of fetal abnormality amounts to some 30 per cent. This entails in practice the requirement for absolute contraindication for coumarins in early pregnancy (first trimester). Finally, possibilities of an acceptable anticoagulant therapy during pregnancy are discussed.
Asunto(s)
Anomalías Inducidas por Medicamentos/patología , Cumarinas/efectos adversos , Complicaciones Hematológicas del Embarazo/tratamiento farmacológico , Tromboflebitis/tratamiento farmacológico , Aborto Espontáneo/patología , Adulto , Cumarinas/uso terapéutico , Epífisis/patología , Femenino , Retardo del Crecimiento Fetal/patología , Humanos , EmbarazoRESUMEN
A card is introduced, which in addition to essential anamnestic data permits registration of entry of diseases, side effects, smoking habits, additional drug intake and results of examinations during steroid medication. The card to be presented whenever a physician is consulted is intended to convey better pill-taking information to other specialists, while also ensuring follow-up of such patients.
Asunto(s)
Anticonceptivos Hormonales Orales/administración & dosificación , Registros Médicos , Anticonceptivos Hormonales Orales/efectos adversos , Femenino , Humanos , RiesgoRESUMEN
Vaginography is recommended to detect and determine the exact location of uretero-vaginal fistulas and vaginal fistulas extending as far as into the upper intestine. Use of a modified Sengstaken probe for instillation of the contrast medium permits meaningful X-ray photographs to be obtained while ensuring definite sealing of the vagina to the outside.
Asunto(s)
Fístula Vaginal/diagnóstico por imagen , Adulto , Diagnóstico Diferencial , Femenino , Humanos , Complicaciones Posoperatorias/diagnóstico por imagen , Radiografía , Fístula Rectovaginal/diagnóstico por imagen , Enfermedades Ureterales/diagnóstico por imagen , Fístula Urinaria/diagnóstico por imagen , Vagina/diagnóstico por imagenRESUMEN
Psychodiagnostic studies were conducted in 100 women with urinary incontinence. The VNPI test proposed by Regel and Schulze, a neurosis screening test, was adopted. Fifty-two of the patients studied revealed test results which were either pathological or called for further elucidation. Pathological VNPI findings were obtained in 23% of the women with stress incontinence, in 48% of those with combined incontinence, and in 85% of the patients with urgency incontinence. The present study suggests that psychodiagnosis is necessary beside comprehensive somatic urinary incontinence diagnosis.
Asunto(s)
Trastornos Psicofisiológicos/psicología , Incontinencia Urinaria/psicología , Nivel de Alerta , Femenino , Humanos , Persona de Mediana Edad , Trastornos Neuróticos/psicología , Inventario de Personalidad , Recurrencia , Incontinencia Urinaria de Esfuerzo/psicologíaRESUMEN
At a woman, at that time only 27 years old, because of a one-sided ovarian tumour, the abdominal hysterectomy with the resection of both appendages had been carried out. At the same time the other ovary macroscopically without pathological findings had been implanted into the Retzius cavity, where later it degenerated tumourously like the histological picture of a cystoma serosum papilliferum proliferans. Since the resection of the second tumour, which was carried out 28 years after the first operation, there has been found no more manifestation of a tumour up to now.
Asunto(s)
Transformación Celular Neoplásica/patología , Cistoadenoma/patología , Neoplasias Ováricas/patología , Ovariectomía , Ovario/trasplante , Complicaciones Posoperatorias/patología , Adulto , Terapia Combinada , Cistoadenoma/cirugía , Femenino , Humanos , Neoplasias Ováricas/cirugía , Ovario/patología , Complicaciones Posoperatorias/cirugíaRESUMEN
Proliferating papillary serous cystadenomas that seldom occur are classified into the group of ovarian tumours of low malignant potential (borderline tumours). The present study includes 33 cases observed in our clinic since 1955. Even though the five-year survival rate being 88% was substantially higher than that for ovarian carcinomas, the prognosis of individual cases cannot be reliably predicted because of the uncertainty as to the biological behaviour in both clinical and histological terms. Consequently, the trend to predominantly radical surgery appears to be a justified approach. Whenever it is desirable to maintain fertility in younger women, conservative surgery would require a unilateral tumour without a ruptured capsule and normal histological findings to be obtained from wedge excision in the opposite ovary.
Asunto(s)
Cistoadenoma/patología , Neoplasias Ováricas/patología , Adulto , Anciano , Castración , Terapia Combinada , Cistoadenoma/cirugía , Femenino , Humanos , Histerectomía , Persona de Mediana Edad , Recurrencia Local de Neoplasia/patología , Neoplasias Ováricas/cirugía , Ovario/patología , PronósticoRESUMEN
Hemotherapy performed in our clinic was investigated in patients operated on in the years 1973 and 1982. A total of 832 operations (638 gynaecological interventions and 194 cesarean sections) were used for evaluation. - Transfusion rates decreased from 72% (1973) to 13% (1982) due to systematic application of crystalloid and colloidal infusions to cases of blood loss of up to 20% of the total blood volume. The percentage of erythrocyte concentrate applied increased from 0.4% (1973) to 42% (1982), while it even reached 80% when related to the total blood transfusions of our clinic. To conclude, strict principles should be adopted in deciding for blood transfusion as well as in purposefully applying blood constituents lost. The advantageous development in the economy of surgery is outlined.
Asunto(s)
Transfusión Sanguínea , Cesárea , Enfermedades de los Genitales Femeninos/cirugía , Histerectomía Vaginal , Histerectomía , Volumen Sanguíneo , Transfusión de Eritrocitos , Femenino , Humanos , Infusiones Parenterales , EmbarazoRESUMEN
Based on the idea that a relationship might exist between cell growth, cell metabolism and functional cell physiological parameters, particularly the bioelectrical membrane properties, the transmembrane potential (TMP) was measured on cultured ovarian tumour cells. After addition of cytostatic drugs to the cell cultures changes in TMP were observed, compared with the controls. The results clearly support that the TMP is a sensitive and objective measuring parameter in pretherapeutic sensitivity tests of tumours.
Asunto(s)
Antineoplásicos/uso terapéutico , Neoplasias Ováricas/tratamiento farmacológico , Células Cultivadas , Resistencia a Medicamentos , Femenino , Humanos , Potenciales de la Membrana/efectos de los fármacos , Neoplasias Ováricas/fisiopatologíaRESUMEN
A report is given on 100 juvenile primigravidae delivered in the period from 1965 to 1973. Course of pregnancy, delivery, postpartum period, rate of premature infants, and perinatal mortality are evaluated. EPH gestosis was observed in juvenile primigravidae at a rate approximately twice that encountered in the total number of all pregnant women. This group of patients is characteristic in that intensive care for pregnant women is required in both out-patient and in-patient treatment. In addition, intensive care for pregnant women has the target of minimising the increased rate of premature infants and the associated elevated perinatal mortality.
Asunto(s)
Trabajo de Parto , Edad Materna , Adolescente , Femenino , Muerte Fetal , Humanos , Mortalidad Infantil , Recién Nacido , Enfermedades del Recién Nacido/etiología , Recien Nacido Prematuro , Trabajo de Parto Prematuro , Embarazo , Extracción Obstétrica por AspiraciónRESUMEN
The paper reports on nine metrorrhexes corresponding to a percentage of 0,056 in the overall number of births. The respective obstetrical anamneses and diagnoses are discussed. Perinatal mortality amounts to 66,7%, maternal deaths did not occur. It is concluded that metrorrhexis has not lost its risks in view of child prognosis, but today's importance of prospective obstetrics enables us to exclude factors causing a rupture to a high degree.