1.
Biochem Biophys Res Commun
; 235(3): 553-6, 1997 Jun 27.
Artículo
en Inglés
| MEDLINE
| ID: mdl-9207194
RESUMEN
Inhibin-betaC is a recently described TGF-beta family member most homologous to inhibin-betaA and inhibin-betaB. By Northern analysis, inhibin-betaC mRNA was detected exclusively in the liver among a large number of adult mouse tissues surveyed. The expression of inhibin-betaC mRNA in adult liver dropped sharply and transiently following partial hepatectomy. At 6 and 12 hours following partial hepatectomy, the levels of inhibin-betaC mRNA were at least 8-fold lower than in control animals. The liver specificity of inhibin-betaC expression and its down-regulation following partial hepatectomy suggest that inhibin-betaC may function as a negative regulator of liver growth.
Asunto(s)
Regulación Enzimológica de la Expresión Génica , Hepatectomía , Hígado/metabolismo , Biosíntesis de Péptidos , Proteínas de Secreción Prostática , Animales , Femenino , Inhibinas/biosíntesis , Cinética , Masculino , Ratones , Ratones Endogámicos , Especificidad de Órganos
2.
Ann N Y Acad Sci
; 718: 232-43; discussion 243-4, 1994 Apr 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-7514379