RESUMEN

The possibility of using antigenic complexes contained in the extracellular slime of P. aeruginosa clinical strains belonging to different serological groups as the components of a chemical vaccine has been revealed. Animal experiments have demonstrated a high immunogenicity of these preparations, as well as their low toxicity. The use of slime antigens stimulates the production of specific antibodies exerting a protective action against infection with homologous P. aeruginosa strains.

Asunto(s)

Antígenos Bacterianos/aislamiento & purificación , Moco/inmunología , Pseudomonas aeruginosa/inmunología , Animales , Anticuerpos Antibacterianos/análisis , Antígenos Bacterianos/análisis , Antígenos Bacterianos/inmunología , Vacunas Bacterianas/inmunología , Vacunas Bacterianas/aislamiento & purificación , Fenómenos Químicos , Química , Inmunización , Ratones , Moco/análisis , Fagocitosis