RESUMEN
Microflora of pathological biosubstrates from 25 patients aged from 18 to 41 years with criminal abortion complications such as sepsis, septic shock, septicemia, and septic pyemia, peritonitis and endometritis of various severity was studied. Obligate anaerobic organisms in association with facultative anaerobes were detected in 84 per cent of the patients. Bacteroids were isolated from operation materials of 36 per cent of the patients. Bacteroids in association with Staphylococcus aureus, peptostreptococci and enterococci were recorded in 16, 8 and 24 per cent of the patients, respectively. Composition of the anaerobic and facultative anaerobic microflora was analyzed in the patients with local and general infections. Antibiotic sensitivity assay of the bacteroids showed that rifampicin, metronidazole, levomycetin (chloramphenicol) and clindamycin were the most active drugs. The use of anaerobic techniques enabled to demonstrate that in patients with purulent septic complications of criminal abortion there prevailed anaerobic-aerobic associations. The results should be considered in treatment of gynecological patients with purulent septic infections.
Asunto(s)
Aborto Criminal , Aborto Incompleto/microbiología , Aborto Séptico/microbiología , Bacterias Anaerobias Gramnegativas/aislamiento & purificación , Adolescente , Adulto , Antibacterianos/farmacología , Femenino , Bacterias Anaerobias Gramnegativas/efectos de los fármacos , Humanos , Pruebas de Sensibilidad Microbiana , Embarazo , Primer Trimestre del Embarazo , Segundo Trimestre del Embarazo , Útero/microbiologíaRESUMEN
Widely varying numbers of endocrine cells were identified in 12 out of 64 cases of uterine cancer in the course of histochemical and electron microscopic examination. Some neoplasms had morphologic features of apudoma of various degree of differentiation, the remaining ones (adenocarcinoma and adenosquamous carcinoma) were identified as tumors of endocrine origin if their cells contained certain specific metabolites most reliably detectable by the argyrophilic method after Grimelius and electron microscopy. The results of the study and literature data suggest that both endocrine and epithelial cells originate from multipotential epithelial stem cells.
Asunto(s)
Transformación Celular Neoplásica/ultraestructura , Enfermedades del Sistema Endocrino/patología , Neoplasias Uterinas/ultraestructura , Adenocarcinoma/metabolismo , Adenocarcinoma/ultraestructura , Adulto , Anciano , Apudoma/metabolismo , Apudoma/ultraestructura , Tumor Carcinoide/metabolismo , Tumor Carcinoide/ultraestructura , Carcinoma/metabolismo , Carcinoma/ultraestructura , Carcinoma de Células Escamosas/metabolismo , Carcinoma de Células Escamosas/ultraestructura , Transformación Celular Neoplásica/metabolismo , Enfermedades del Sistema Endocrino/metabolismo , Femenino , Histocitoquímica , Humanos , Microscopía Electrónica , Persona de Mediana Edad , Pronóstico , Neoplasias del Cuello Uterino/metabolismo , Neoplasias del Cuello Uterino/ultraestructura , Neoplasias Uterinas/metabolismoRESUMEN
Four morphofunctional cell types are distinguished ultrastructurally in the glandular epithelium of endometrium with dyshormonal glandular hyperplasia of the medium proliferative stage: proliferating, secreting, ciliary, endocrine. The cells of every type may undergo degeneration. The possibility of the cell proliferation with predominantly endocrine differentiation is noted.