RESUMEN
AIM: Study the state of intestine microbiocenosis in patients with chronic pancreatitis, give comparative evaluation of diagnostic significance of bacterial and gas-liquid chromatography analysis. MATERIALS AND METHODS: 96 patients with chronic pancreatitis (CP) were examined bacteriologically for dysbacteriosis. In parallel in 42 individuals gas-liquid chromatography analysis (GLC-analysis) was carried out. RESULTS: During bacteriological examination in 93.7% of patients various dysbiotic disorders were detected. The main indicators of GLC-analysis---anaerobic index, cumulative content of volatile fatty acids and their isoforms also gave evidence on imbalance of intestine microflora. GLC-analysis as a rule confirmed the data of bacteriological examination. CONCLUSION: During parallel use ofbacteriological and gas-liquid chromatography analysis in almost all the CP patients intestine dysbacteriosis of various degree of intensity was detected. Combined use of these methods increases effectiveness of examination.
Asunto(s)
Bacterias/aislamiento & purificación , Disbiosis/microbiología , Intestinos/microbiología , Pancreatitis Crónica/microbiología , Adulto , Bacterias/clasificación , Bacterias/patogenicidad , Cromatografía de Gases/métodos , Disbiosis/patología , Heces/microbiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pancreatitis Crónica/patologíaRESUMEN
Heterogeneity of the metabolic syndrome in diabetes mellitus serves as an indication for plasmapheresis in therapy of disease. The effect of plasmapheresis on the indices of carbohydrate, lipid metabolism and immune homeostasis was studied in 30 patients with primary diabetes mellitus. Microstructure of the surface of dried blood serum drops was investigated in parallel with it. The control group included 20 patients who were not given plasmapheresis and 20 healthy subjects. A positive effect of plasmapheresis on the above indices was observed. Its approximate effect on the patients blood serum composition was shown.