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1.
Chinese Journal of Neuromedicine ; (12): 389-392, 2011.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1033248

RESUMEN

Objective To study the relationship between D-wave of thc spinal motor evoked potential and hindlimb motor function status (myodynamia) of rabbits with experimental spinal cord injury. Methods Forty-five rabbits were randomly divided into a control group and 8 injured groups (receiving Allen's injury of50, 75, 100, 125, 150, 175, 200 and 250 gcf, respectively). The myodynamia of hindlimbs and the latency and amplitude of D-wave of the spinal motor evoked potential were recorded right after the injury and in the 4th week of injury, respectively. Simultaneously in the 4th week of injury,the rabbits' spinal sections were stained with neurofilament (NF) immunohistochemistry and their pathological morphologies were observed; and optical densities of NF were measured. Statistic analysis of correlation between myodynamia of hindlimbs and latency and amplitude of D-wave was performed.Results A statistic linear correlation was found between amplitudes declination of D-wave of the spinal motor evoked potential and modified Tarlov's scores right after the injury and in the 4th week of injury (R2=0.98, P<0.00, regression curve: Y=0.33+4.82X; R=0.99, P<0.001, regression curve: Y=0.04+0.5 1X),but no statistical correlation was noted between myodynamia and the latency of D-wave of the spinal motor evoked potential at the same time periods(R2=-0.097, P=0.573; R2=-0.165, P=0.337). And the optical density of NF decreased following the amplitude declination of D-wave of the spinal motor evoked potential with linear correlation (R2=0.87, P<0.001, regression curve: Y= 0.12+0.58X).Conclusion Amplitude declination of D-wave of the spinal motor evoked potential could be used to evaluate the severity of dyskinesia in the injured spinal cord.

2.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-330821

RESUMEN

<p><b>OBJECTIVE</b>To study the relationship between muscle motor evoked potentials (MEP) and hindlimbs motor function in rabbits with spinal cord injury.</p><p><b>METHODS</b>Forty-five rabbits were randomly divided into 9 groups, including one control group and 8 injured groups (receiving Allen's injury of 0, 50, 75, 100, 125, 150, 175, 200, or 250 gcf). Hindlimb strength and muscle MEP were recorded at the 1st day and 4th week postoperatively. At 4 weeks after spinal section, the spinal cord tissue was sampled for histological examination with HE staining and immunohistochemistry with anti-NF antibody of the corticospinal tract fibers.</p><p><b>RESULTS</b>During the operation, MEP showed an all-or-none pattern with significant correlations to postoperative optical density of NF and postoperative hindlimb motor function. The latency prolongation of the muscle MEP at the 4th week showed a linear correlation to the hindlimb Tarlov's score, whereas the MEP amplitude was not correlated to postoperative hindlimb motor function.</p><p><b>CONCLUSIONS</b>The all-or-none pattern of muscle MEP can be used to evaluate the severity of spinal cord injury.</p>


Asunto(s)
Animales , Conejos , Potenciales Evocados Motores , Miembro Posterior , Tractos Piramidales , Traumatismos de la Médula Espinal
3.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1032667

RESUMEN

Objective To investigate the clinical and neuroimaging features and microsurgical approaches of intracranial cavernous angiomas (CA). Methods The clinical and neuroimaging features and mierosurgical approaches were analyzed retrospectively in 189 cases of intracranial CA. Results Of the 189 cases, 183 presented with CA in the cerebral parenchyma and clinical manifestations including predominantly headache, epilepsy, and hemorrhage, and were managed by radical resection of the CA. The other 6 cases showed intracranial CA in the middle cranial fossa, for which radical CA resection was performed in 5 cases and biopsy in 1 case. Conclusion Microsurgeries are safe and effective for treatment of intracranial CA and may achieve good clinical outcomes.

4.
Chinese Journal of Neuromedicine ; (12): 929-931, 2009.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1032864

RESUMEN

Objective To analyze the clinical diagnosis,treatment and prognosis of rhabdoid meningioma.Methods Two cases of rhabdoid meningioma treated in our department were analyzed retrospectively,and the relevant literatures were reviewed.Results Both of the two patients underwent complete meningioma removal under microscope(Simpson grade I)without postoperative radiotherapy or chemotherapy.The two patients were followed up for 2 months and 2 years.One patient experienced meningioma recurred 2 years after the operative,and died due to refusal of a second operation.The other patient died of systemic complications secondary to postoperative intracranial infection.Conclusion The preoperative diagnosis of rhabdoid meningioma can be difficult,and surgical meningioma removal remains the primary choice of treatment.The patients often experience meningioma recurrence shortly after the operation with poor prognosis.Early postoperative radiochemotherapy may prove beneficial in prolonging the survival of patients.

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