RESUMEN
According to examination, with the help of emission spectrum analysis method, of 24 cadets-athletes of different specialization it was determined that during physical exercise in summer and in winter loss of ferrum and copper with excrements exceeded the intake if these microelements with food. The next day rise of impaction of microelements and decrease of excretion. But despite the positive balance of ferrum and copper, spend of these microelements during physical exercise wasn't compensated for the day of rest. That is why there is a possibility of microelement deficit.
Asunto(s)
Cobre/metabolismo , Ejercicio Físico/fisiología , Hierro/metabolismo , Personal Militar , Descanso/fisiología , Deportes/fisiología , Adolescente , Adulto , Cobre/administración & dosificación , Cobre/orina , Encuestas sobre Dietas , Heces/química , Humanos , Hierro/administración & dosificación , Hierro/orina , Federación de Rusia , Estaciones del Año , Adulto JovenRESUMEN
Conducted with the participation of 50 students of military educational study the effect of various vitamin and mineral complexes for the provision by the body naturally iron, copper and manganese on the immune and physical status. Found that diets enriched BMV was accompanied by a significant delay in the micro-elements, mainly iron, which indicates a deficiency of these bioelements in chickens Santo during the summer. Under the influence of vitamin-mineral complexes significantly increased rates of natural and specific immunity. As the delay increases significantly increased iron medical indicators of immunological reaction efficiency and physical performance.
Asunto(s)
Inmunidad Innata/efectos de los fármacos , Personal Militar , Aptitud Física , Oligoelementos/sangre , Oligoelementos/uso terapéutico , Vitaminas/uso terapéutico , Adolescente , Adulto , Linfocitos B/citología , Linfocitos B/inmunología , Cobre/administración & dosificación , Cobre/sangre , Cobre/uso terapéutico , Suplementos Dietéticos , Humanos , Inmunidad Celular/efectos de los fármacos , Inmunidad Humoral/efectos de los fármacos , Hierro/administración & dosificación , Hierro/sangre , Hierro/uso terapéutico , Manganeso/administración & dosificación , Manganeso/sangre , Manganeso/uso terapéutico , Aptitud Física/fisiología , Linfocitos T/citología , Linfocitos T/inmunología , Oligoelementos/administración & dosificación , Vitaminas/administración & dosificación , Adulto JovenRESUMEN
AIM: To comparatively evaluate the efficiency of preventive treatment with various iron preparations on copper, manganese, and iron metabolic features in adult athletes. SUBJECTS AND METHODS: Forty adult highly qualified sambo wrestlers were examined and divided into 4 groups of 10 persons in each. Group 1 athletes took iron-containing Sorbifer Durules in combination with ascorbic acid; Group 2 received Ferro Gradumet Vitamin C; Group 3 had Hemofer and ascorbic acid; Group 4 took ascorbic acid tablets. The latter group served as a control. Blood samples (15-20 ml) to be tested were taken at the beginning and end of 2-week use of iron preparations. The daily balance of iron, copper, and manganese was estimated following 7-day intake of these preparations. RESULTS: The use of iron-containing preparations in combination with ascorbic acid was ascertained to be accompanied by an increment in the plasma concentration of iron and blood corpuscles, indicating an increased need for this biotic and its deficiency in athletes. When the dose of iron was increased in the iron preparations, there was a substantial rise in the excretion of copper, manganese in particular, through the gastrointestinal tract and kidney and a negative balance of these trace elements in the body. CONCLUSION: Dietary addition of foods containing large amounts of ferrous iron, copper, and manganese is indicated for athletes exposed to higher intensity exercises.
Asunto(s)
Ácido Ascórbico , Cobre , Compuestos de Hierro , Trastornos del Metabolismo del Hierro/prevención & control , Hierro , Manganeso , Adulto , Ácido Ascórbico/administración & dosificación , Ácido Ascórbico/farmacocinética , Atletas , Cobre/análisis , Cobre/metabolismo , Dietoterapia/métodos , Relación Dosis-Respuesta a Droga , Quimioterapia Combinada , Femenino , Humanos , Hierro/metabolismo , Compuestos de Hierro/administración & dosificación , Compuestos de Hierro/farmacocinética , Deficiencias de Hierro , Trastornos del Metabolismo del Hierro/etiología , Trastornos del Metabolismo del Hierro/metabolismo , Masculino , Manganeso/análisis , Manganeso/metabolismo , Tasa de Depuración Metabólica/efectos de los fármacos , Prevención Primaria/métodos , Análisis Espectral/métodos , Deportes/fisiología , Oligoelementos/análisis , Oligoelementos/metabolismo , Vitaminas/administración & dosificación , Vitaminas/farmacocinéticaRESUMEN
AIM: To measure levels of several types of antibacterial antibodies in preparations of normal human immunoglobulin as well as in samples of donor sera obtained in 1965 and 2009. MATERIALS AND METHODS: Five batches of human normal immunoglobulin manufactured in 1965 and five batches manufactured in 2009 as well as 77 and 28 blood serum samples respectively were tested by agglutination assay for the presence of antibodies to enterobacteria, Brucella species, tularemia agent, Rickettsia burnetii, Rickettsia prowazekii, and several species of opportunistic bacteria. RESULTS: Higher antibody titers to Salmonella typhi, Salmonella paratyphi A and B, Salmonella enteritidis, Salmonella typhimurium, Shigella flexneri and Shigella sonnei were revealed in immunoglobulin preparations and donor sera obtained in 1965 compared to that obtained in 2009. There was no difference in antibody titers to Shigella boydii, Salmonella choleraesuis, Escherichia coli O-55, Pseudomonas aeruginosa, Proteus vulgaris, Serratia marcescens and E. coli. Antibodies to Brucella species, tularemia agent, R. burnetii, R. prowazekii were not detected in normal human immunoglobulin. CONCLUSION: Decrease of antibody levels to several pathogenic enterobacteria in human immunoglobulin preparations as well as in sera of donors for 40 years could be linked with decrease of number of immunized persons, changes in circulation of pathogenic bacteria, decrease of rate of asymptomatic infections. Stability of antibody titers to opportunistic bacteria is a rationale to use them for assessment of humoral immunity function.
Asunto(s)
Anticuerpos Antibacterianos/análisis , Infecciones por Enterobacteriaceae/sangre , Enterobacteriaceae/inmunología , Inmunoglobulinas/química , Suero/inmunología , Anticuerpos Antibacterianos/sangre , Donantes de Sangre , Infecciones por Enterobacteriaceae/inmunología , Humanos , Federación de RusiaRESUMEN
In was defined that 2-week intake by senior school pupils of iron-containing supplements combined with an ascorbic acid was followed by a significant increase of iron concentration in plasma and formal blood elements, hemoglobin and erythrocytes level, increase of vitamin C provision and physical performance efficiency at simultaneous decrease of copper and manganese content in blood plasma.
Asunto(s)
Ácido Ascórbico/farmacología , Cobre/sangre , Compuestos de Hierro/farmacología , Hierro/sangre , Manganeso/sangre , Deportes , Adolescente , Ácido Ascórbico/administración & dosificación , Suplementos Dietéticos , Humanos , Compuestos de Hierro/administración & dosificación , Compuestos de Hierro/efectos adversos , Masculino , Aptitud Física/fisiologíaRESUMEN
Examinations of 49 athletes aged 18 to 22 years established that 2-week intake of vitamin-mineral complexes (VMC) caused a significant increase in the concentrations of iron, copper, and magnesium in plasma and blood corpuscles and a rise in the content of hemoglobin, red blood cells, and body vitamin C provision, and exercise performance during the positive balance of the above trace elements (TE), which is indicative of their deficiency in the body in summer. Supplementation of TE to diets showed that increasing the dose of minerals as components of VMC substantially reduced the percentage assimilation of iron, copper, and magnesium as constituents of preparations and increased fecal and urinary ME excretion.
Asunto(s)
Anemia Ferropénica/prevención & control , Deportes , Oligoelementos/uso terapéutico , Vitaminas/uso terapéutico , Adolescente , Adulto , Anemia Ferropénica/sangre , Rendimiento Atlético/fisiología , Rendimiento Atlético/tendencias , Recuento de Eritrocitos , Eritrocitos/citología , Hemoglobinas/análisis , Humanos , Masculino , Estaciones del Año , Oligoelementos/administración & dosificación , Oligoelementos/sangre , Resultado del Tratamiento , Vitaminas/administración & dosificación , Adulto JovenRESUMEN
The studies of 39 high-grade unarmed self-defense sportsmen established that enrichment of diets with a complex of vitamins and trace elements in combination with adaptogens in the summer period of training was followed by an increase in the concentration of iron in the plasma and blood corpuscles and in the count of red blood cells, the supply of vitamin C, and the level of efficiency. With a significantly improved iron metabolism, the parameters of immunological responsiveness substantially increased. At the same time the greatest increase in the proportion of performance and natural, cellular, and humoral immunity was observed in the sportsmen taking micronutrients with eleutherococcus, and ginseng in particular, as compared with those using a vitamin-micronutrient complex with dibasol.
Asunto(s)
Anemia Ferropénica/prevención & control , Competencia Profesional , Deportes , Anemia Ferropénica/tratamiento farmacológico , Anemia Ferropénica/metabolismo , Hemoglobinas/metabolismo , Humanos , Linfocitos T/metabolismo , Oligoelementos/metabolismo , Vitaminas/uso terapéuticoRESUMEN
Microbiology, X-ray study, and bronchoscopy, including the examination of bronchoalveolar lavage and histology of thransbronchial lung biopsy specimens have proven to be of the greatest informative value in the differential diagnosis of different forms of systemic vasculitis and tuberculosis in 52 patients. Focal pulmonary tuberculosis was detected in the phase of S(II) infiltration on the right in a patient with rheumatic arthritis; Mycobacterium tuberculosis was bacterioscopically detected. The patient underwent specific antituberculous therapy that provided beneficial effects.
Asunto(s)
Tuberculosis Pulmonar/diagnóstico , Vasculitis/diagnóstico , Adulto , Anciano , Broncoscopía , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Radiografía Torácica , Estudios RetrospectivosRESUMEN
Examinations of 29 female students of a study medical group have ascertained that daily addition of vitamins (ascorutin, thiamin, riboflavin, pyridoxine, cyanocobalamin, and folic acid) to a diet resulted in a slight enhancement in trace element metabolism and hence in an increase in the intestinal and renal excretion of iron, copper, and manganese. Two-week dietary supplement of vitamins in combination with trace elements (iron, copper, and manganese) caused a considerable retention of iron and manganese concurrently with a higher excretion of copper from the body. At the same time, the higher rate of hemopoiesis and the elevated plasma levels of iron and formed blood elements, and the rise in non-specific responsiveness and physical fitness were more noticeable as compared to their normal values. A significant positive correlation was found between the direct and indirect indices of iron metabolism on one hand and the parameters of natural immunity defense and physical fitness on the other.
Asunto(s)
Suplementos Dietéticos , Inmunidad Innata , Deficiencias de Hierro , Oligoelementos/administración & dosificación , Vitaminas/administración & dosificación , Adolescente , Adulto , Actividad Bactericida de la Sangre , Proteínas del Sistema Complemento/análisis , Interpretación Estadística de Datos , Femenino , Humanos , Hierro/sangre , Hierro/metabolismo , Aptitud Física , Factores de Tiempo , Oligoelementos/metabolismo , Vitaminas/metabolismoRESUMEN
Questionnaire survey of 127 female medical students from a study group indicated that the dietary levels of proteins, particularly animal ones, as well as fats, carbohydrates, vitamins (C, B1, B2, and B6), and trace elements (potassium, calcium, magnesium, phosphorus, iron, copper, and manganese) was much lower in spring than in autumn and they did not correspond to the recommended physiological requirements for these nutrients. Examining the immunological responsiveness in the female students revealed seasonal variations of some cellular and humoral immunological parameters. The reduction in the level of T lymphocytes of serum immunoglobulins (mainly immunoglobulins G) and in the number of circulating immune complexes in spring as compared with autumn was associated with the significant increase of the relative and absolute counts of B lymphocytes.
Asunto(s)
Linfocitos B/inmunología , Inmunoglobulinas/inmunología , Estado Nutricional , Linfocitos T/inmunología , Adolescente , Adulto , Femenino , HumanosRESUMEN
The content of iron in foods consumed by schoolchildren in winter was found to be much lower than the recommended one. In summer dietary iron consumption proved to be twice less than that in winter and 3 times less than the physiological allowance for this age. The indices of cellular and humoral immunity during a school year changed in diametrically opposite direction: increases in the count of T and B lymphocytes in winter and, especially, spring months were attended by a concurrent and significant reduction in the content of immunoglobulins G, M, and A. There was a significant rise in the indices of phagocytosis in winter as compared to autumn and their drastic reduction in spring as compared to winter.
Asunto(s)
Hierro/sangre , Estaciones del Año , Adolescente , Formación de Anticuerpos/inmunología , Femenino , Humanos , Inmunidad Celular/inmunología , Inmunoglobulina A/sangre , Inmunoglobulina G/sangre , Inmunoglobulina M/sangre , Hierro/administración & dosificación , MasculinoRESUMEN
The paper analyzes the clinical manifestations of adenogenic tuberculosis, the methods of its diagnosis and treatment in 44 patients (15 males and 29 females) aged 18 to 75 years. The signs of an active tuberculous process were identified in the bronchus and lung of 33 patients and the remaining patients had posttuberculous adaptogenic changes. A bronchological study revealed infiltrative bronchial tuberculosis in 15 patients, bronchial fistula in 4, inflammatory and cicatrical stenoses in 22, broncholiths in 2, and nonspecific bronchitis in 5. The patients with specific active changes received antituberculous chemotherapy with 4 drugs; those with nonspecific lesions had antirecurrent chemotherapy and, in case of an exacerbation of nonspecific recurrent pneumonias and chronic bronchitis, used antibiotics mainly as inhalants.
Asunto(s)
Enfermedades Bronquiales/complicaciones , Tuberculosis Pulmonar/etiología , Tuberculosis Pulmonar/patología , Adolescente , Adulto , Anciano , Antituberculosos/uso terapéutico , Enfermedades Bronquiales/tratamiento farmacológico , Broncodilatadores/uso terapéutico , Quimioterapia Combinada , Expectorantes/uso terapéutico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Tuberculosis Pulmonar/tratamiento farmacológicoRESUMEN
Examining 17 untrained female students and 110 trained ones indicated that moderate exercises as aerobic ones did not exert a great impact on most parameters of cellular and humoral immunity. Exclusions were higher absolute counts of B lymphocytes in the trained students than those in the untrained ones at the end of an academic year (in spring). Despite their activity, all the female students were found to have seasonal variations in some immunological parameters. Among other things, the content of immunoglobulins (primarily classes G and A) dropped in winter and particularly in spring as compared to autumn; on the contrary, the parameters of phagocytosis significantly increased in winter versus autumn, then fell in spring months as compared to winter; vive versa, the count of circulating immune complexes substantially reduced in winter as compared with autumn, then showing a trend for an increase in spring, at the end of an academic year.
Asunto(s)
Linfocitos B/inmunología , Inmunoglobulinas/inmunología , Estudiantes , Linfocitos T/inmunología , Femenino , HumanosAsunto(s)
Tuberculosis Ganglionar/diagnóstico , Adolescente , Adulto , Biopsia con Aguja , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mycobacterium tuberculosis/aislamiento & purificación , Tuberculosis Ganglionar/diagnóstico por imagen , Tuberculosis Ganglionar/patología , UltrasonografíaRESUMEN
The results of a long-term (5-10 year) follow-up were studied in 109 patients with alveolitis, including 89 with EAA and 20 with IFA. A variety of treatments were applied. The predominant treatments were hormonal therapy supplemented by plasmapheresis, physiotherapy, oxygen therapy, etc. A follow-up of patients with alveolitis was made by 3 groups. Group 1 was compensated--Stage 0; Group 2, subcompensated--Stage II; Group 3, decompensated--Stage III. The control periods and scope of examinations were defined for each group. The Regulations governing the prophylactic medical examination of patients with alveolitis were worked out. Among patients with EAA, good results, such as improvement and stabilization of the process, were observed in 34.8% of cases, poor results, such as recurrences were in 53.6%, death rates were 3%. Among patients with IFA, good results were achieved in 15% of cases, recurrences and progression were in 10 and 30.7%, respectively, death rates were 40%.
Asunto(s)
Adyuvantes Inmunológicos/uso terapéutico , Antituberculosos/uso terapéutico , Broncodilatadores/uso terapéutico , Servicios Preventivos de Salud , Fibrosis Pulmonar/tratamiento farmacológico , Adulto , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fibrosis Pulmonar/diagnóstico por imagen , Fibrosis Pulmonar/prevención & control , Radiografía , TiempoRESUMEN
Examinations of 22 young unarmed self-defence sportsmen and 18 untrained schoolchildren indicated that the indices of nonspecific immunity defence--serum complement and lysozyme--depended on a season rather than on a motor activity regimen. Changes in the concentrations of hemoglobin and plasma iron were also obviously seasonal. These indices were the least in spring and winter as compared to autumn and winter. Blood iron levels were higher in the young sportsmen than in the untrained schoolchildren at all stages of a follow-up. There was a direct relationship between direct and indirect parameters of iron exchange, physical fitness, and nonspecific protection factors. In all teenagers, the activity of serum lysozyme and complement was directly related to the plasma level of iron and the school children's physical fitness was closely correlated with plasma and blood cell iron concentrations.
Asunto(s)
Proteínas del Sistema Complemento/análisis , Estado de Salud , Hierro/sangre , Muramidasa/sangre , Aptitud Física , Adolescente , Factores de Edad , Humanos , Estaciones del Año , DeportesRESUMEN
Sarcoidosis with atypical clinical manifestations and a poor course accounts for 5.6% (78 individuals per 1400 patients). The paper describes the atypical manifestations of sarcoidosis (fever, hypereosinophilia, lymphocytosis, etc.) and its poor course, which are similar to those of lymphoproliferative diseases, fibrosing alveolitis-type sarcoidosis, infiltrative pneumonic forms). Each of the above manifestations has complex differentially diagnostic aspects.
Asunto(s)
Sarcoidosis/patología , Diagnóstico Diferencial , Humanos , Pronóstico , Sarcoidosis/diagnósticoRESUMEN
On investigating of 60 healthy female students with use of a questionnaire method, it was found out what amount of basic nutrients, such as: proteins (especially those of animal origin), animal fats, hydrocarbons, vitamins (C, B1, B2, B6) mineral elements (calcium, potassium, magnesium and phosphorus) in students nourishment was lower in the spring than in the fall. Both in the spring and in the fall this amount was not appropriate for recommended physiological nourishment standards. On investigating of immunological reactivity of these students season's fluctuations for some indexes of cellular and humoral immunity were found. Lowering of T-lymphocytes lever together with lowering of blood immunoglobulines (especially those of G-calss) and lowering of lever of immunological complexes, circulating in the blood in spring comparing to the fall combinated with growth of B-lymphocytes lever.