RESUMEN

Decarboxylative alkylation or acylation reactions of simple pyrimidines have been developed in aqueous media. Using aliphatic carboxylic acids or 2-oxocarboxylic acids and pyrimidines as substrates and silver as the catalyst, the 4-substituted alkyl or acyl pyrimidines were isolated in moderate to good yields.

Asunto(s)

Ácidos Carboxílicos/química , Pirimidinas/síntesis química , Plata/química , Catálisis , Descarboxilación , Estructura Molecular , Pirimidinas/química , Agua/química