RESUMEN

Enoxaparin sodium is a low molecular weight heparin (LMWH) used to treat and prevent deep venous thrombosis (DVT). The common complications related to the use of heparin are bleeding, allergic reaction, and osteoporosis. A less common complications are thrombocytopenia and thromboembolism that may not be generally recognized. We present a case of low molecular weight (LMW) heparin-induced thrombocytopenia (HIT) causing stroke, lower extremity arterial occlusion, and skin necrosis. Monitoring the platelet count is essential for early diagnosis of HIT. All patients who undergo heparinization should have a baseline platelet count done before the regimen is started and should be monitored closely especially during the first weeks of treatment.

Asunto(s)

Arteriopatías Oclusivas/etiología , Heparina/efectos adversos , Extremidad Inferior/irrigación sanguínea , Extremidad Inferior/patología , Accidente Cerebrovascular/etiología , Trombocitopenia/inducido químicamente , Trombocitopenia/complicaciones , Anciano , Arteriopatías Oclusivas/cirugía , Embolectomía , Femenino , Heparina de Bajo-Peso-Molecular/efectos adversos , Humanos , Imagen por Resonancia Magnética , Necrosis , Accidente Cerebrovascular/diagnóstico , Resultado del Tratamiento

RESUMEN

Objectives. Multiple sclerosis (MS) is an inflammatory autoimmune disorder of the central nervous system (CNS). Since a correlation between gluten intake and incidence of MS had been reported, the relationship of antigliadin antibodies and MS was debated. Case Report. We report the case of a 45-year-old female MS patient who is under interferon treatment. After seven years of monitoring, during her routine gastroenterological assessment, she was diagnosed with celiac disease. Conclusion. Beside the neurological manifestations that have been demonstrated in about 10% of celiac disease (CD) patients, white-matter abnormalities in brain MRI are uncommon and controversial. But in the literature, MS seems to be associated with CD as in our patient. We suggest that MS patients with gastroenterological complaints should undergo an assessment for CD.