RESUMEN

This study aims to assess the effectiveness of conservative treatment for chalazion in pediatric patients. The authors retrospectively reviewed 101 chalazions in 91 children aged younger than 15 years at the authors' clinic. Patients were divided into 3 groups by their ages at the time of conservative or surgical treatment: 30 patients aged 2 and under (group A), 38 patients aged 3 to 6 (group B), and 23 patients aged 7 to 15 (group C). Initially, conservative treatment was administered, then incision and curettage were performed if it proved ineffective. Data included sex, age, number of lesions, position of lesions, size of lesions, time to resolution after treatment, and presence of complications for each group; comparative analysis was conducted. The success rate of conservative treatment was 85.7% (78/91): 96.7% (29/30) in group A, 86.8% (33/38) in group B, and 69.7% (16/23) in group C (P = 0.022). The mean age of the patients and the mean lesion size showed a significant difference between the conservative group and the surgery group (P = 0.047 and 0.009, respectively). Conservative treatment of chalazion is an effective first-line treatment option for uncomplicated and small chalazion in pediatric patients. The authors should consider starting patients on a trial of conservative therapy versus invasive therapy based on the size of the lesion, the duration of conservative treatment, and age.

RESUMEN

PURPOSE: To compare the efficacy of a 0.15% HA with that of 0.1% HA eye drops for DES after cataract surgery. METHODS: This study was double blinded, randomized and prospective study, and conducted in 69 participants (70 eyes) from Pusan National University Yangsan Hospital and executed from February 1, 2022 to November 30, 2022. Participants were adult cataract patients with normal lid position, not suffering from any other ocular disease and not meet the exclusion cirteria of clinical trial. Participants were randomly divided into two groups: 35 participants (17 males and 18 females) in the 0.1% HA group and 34 participants (19 males and 15 females) in the 0.15% HA group, receiving treatment six times daily for 6 weeks following cataract surgery. Subjective and objective assessments were performed at preoperative and postoperative visits, including ocular surface disease index score, tear break up time, corneal staining score, Schirmer's I test score, lipid layer thickness), meiboscore, and biochemical analysis of the eye drops. RESULTS: Throughout the study, the postoperative ocular surface disease index score was significantly lower in the group receiving 0.15% hyaluronic acid than in the group receiving 0.1% hyaluronic acid. Additionally, the postoperative ocular surface disease index score showed a significant positive correlation with the postoperative use of 0.15% hyaluronic acid and the preoperative Schirmer's I test score. In multivariate analysis, treatment with 0.15% hyaluronic acid and the preoperative ocular surface disease index score were significant independent parameters affecting the postoperative ocular surface disease index score. CONCLUSION: The use of 0.15% hyaluronic acid is recommended for its potential advantages in alleviating symptoms following cataract surgery, making it a viable alternative to traditional 0.1% hyaluronic acid treatment. TRIAL REGISTRATION: ISRCTN95830348.

Asunto(s)

Extracción de Catarata , Ácido Hialurónico , Glándulas Tarsales , Soluciones Oftálmicas , Humanos , Ácido Hialurónico/administración & dosificación , Ácido Hialurónico/uso terapéutico , Masculino , Femenino , Anciano , Extracción de Catarata/efectos adversos , Estudios Prospectivos , Persona de Mediana Edad , Glándulas Tarsales/efectos de los fármacos , Glándulas Tarsales/metabolismo , Soluciones Oftálmicas/administración & dosificación , Método Doble Ciego , Lípidos , Resultado del Tratamiento

RESUMEN

Backgroud: To analyze the factors associated with surgical outcomes after bilateral rectus recession (BLR) in children with intermittent exotropia (IXT). Methods: A retrospective study was performed on 125 patients who had all received preoperative patch treatment with a ≥1 year follow-up. The surgical outcomes were grouped as success (esodeviation ≤5 PD to exodeviation ≤10 PD) or failure (esodeviation >5 PD or exodeviation >10 PD) according to the angle of deviation at 1 year postoperatively. The patients' magnitude of exodeviation, near and distant stereoacuity, and 3-mo patch responses were assessed. The factors associated with the surgical outcomes were determined using univariate and multivariate analyses. Results: Of the 125 patients, 102 (81.6%) and 23 (18.4%) were assigned to the success and failure groups, respectively. According to the univariate analysis, the absence of anisometropia, a smaller preoperative near exodeviation, a better near stereopsis, a smaller magnitude of deviation on day 1 postoperatively, and response to patching were significantly associated with surgical success for IXT after 1 year. In the multivariate analysis, distant esotropic deviation on day 1 postoperatively and response to patching were the factors affecting successful surgical outcomes. Conclusions: Esotropic distant deviation on day 1 postoperatively is a prognostic factor for favorable surgical outcomes. Preoperative patching could be a factor influencing surgical success in children with IXT.