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AIM To establish a quantitative analysis of multi-components by single-marker(QAMS)method for the simultaneous content determination of gastrodin,parishin E,syringin,parishin B,parishin C,ferulic acid,parishin A,buddleoside,harpagoside and cinnamic acid in Tianma Toufengling Capsules.METHODS The analysis was performed on a 30℃thermostatic GL Science InertsilTM ODS-3 column(150 mm×4.6 mm,5 μm),with the mobile phase comprising of acetonitrile-0.1%phosphoric acid flowing at 1.0 mL/min in a gradient elution manner,and the detection wavelengths were set at 220,280 nm.Syringin was used as an internal standard to calculate the relative correction factors of the other nine constituents,after which the content determination was made.RESULTS Ten constituents showed good linear relationships within their own ranges(r≥0.999 7),whose average recoveries were 98.53%-102.22%with the RSDs of 1.26%-2.68%.The result obtained by QAMS approximated those obtained by external standard method.CONCLUSION This accurate and specific method can be used for the quality control of Tianma Toufengling Capsules.
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The paper explains challenge and influence of the building of safe hospital against the "Intemet + " background,and discusses the countermeasures including strengthening personal information protection,the third party supervision,public opinion monitoring,talent cultivation and other aspects,in order to promote rapid development of safe hospital building.
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OBJECTIVE: To understand the characteristics of schistosome cercarial infested water contact of residents in Poyang Lake endemic areas after the operation of Three Gorges Project, so as to provide the evidence for formulating a well-directed control strategy. METHODS: The residents in two villages in schistosomiasis endemic areas were selected and surveyed for their activities of infested water contacts by questionnaire. RESULTS: The proportion and frequency of infested water contacts of residents in Poyang Lake region were high and the average rate of infested water contacts was 69.77%, and 98.96% of infested water contacts occurred in spring, summer and autumn. The main ways of infested water contacts were fishing/swimming/playing for adult men, washing clothes/fishing for adult women, and swimming/playing for school children, respectively. The rates of infested water contacts were 73.33%, 71.63% and 61.87% in adult men, women and school children, respectively. The frequencies of infested water contacts > 1 time/week, 1 time/week-1 time/month, and < 1 time/month were 62.61%, 23.74% and 13.66% respectively. CONCLUSIONS: The infested water contacts mainly occurs in spring, summer and autumn, and the main way of infested water contacts was fishing. Farming and mowing grass, which had been the primary way, now become the secondary way for the adult residents.