RESUMEN

Objective To compare the clinical efficacy of fungal vaginitis treated with oral medication and external drug. Methods A total of 102 cases with fungal vaginitis were collected from March 2014 to March 2015 in our hospi-tal, they were divided into group A and group B, each group had 51 cases. Group A was treated with oral medications, oral nystatin tablets and fluconazole tablets; Group B was treated with topical medications, Nifuratel-nystatin vaginal suppositories vaginal drugs was used, the clinical efficacy, the improvement of clinical symptoms and signs, recurrence of two groups were compared. Results The total effective rate and secretions negative rate in group A at the end of treatment had no significant difference compared with group B (P>0.05). The genital itching, burning, vaginal secretions decrease or disappearance time of group A were longer than group B, secretions negative situation after 4 weeks of treatment was higher than group B, the recurrence rate was lower than group B(P<0.05). Conclusion Nystatin oral tablets and topical Nifuratel-Nystatin vaginal suppository in treatment of fungal vaginitis have similar clinical effects, topical treatment can quickly improve the clinical symptoms and shorten the treatment time, the recent effect is good, oral treatment relapse rate is lower, and has better long-term outcome, the proposed comprehensive application in order to achieve the best therapeutic effect.