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OBJECTIVE: To examine expression of survivin and Bcl-2 in eutopic endometrium with endometriosis and without endometriosis by immunohistochemical stain. METHODS: Expression of survivin and Bcl-2 was immunohistochemically investigated in eutopic endometrium with endometriosis (n=30, study group I; laparoscopy-proved endometriosis, study group II; adenomyosis) or without endometriosis (n=34, control group). The score of immunohistochemical staining was evaluated semi-quantitative method modified by Sinicrope and Lu. Statistical analyses was carried out using one-way ANOVA with Turkey test. RESULTS: Survivin expression was significantly higher in nucleus of glandular epithelium of eutopic endometrium with endomtriosis compared to that without endometriosis (p<0.05). Increased expression of Bcl-2 was found in glandular epithelium of eutopic endometrium with endometriosis than without endometriosis, but there was no significantly difference. CONCLUSION: Our findings suggest that increased survivin expression may contribute to survival of endometriosis. Moreover, survivin could play an important role in pathogenesis of endometriosis.
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Femenino , Endometriosis , Endometrio , Epitelio , TurquíaRESUMEN
OBJECTIVE: To determine that epidural anesthesia need not increase Cesarean delivery rates and prolong labor. METHODS: From December 1999 to May 2002, 1,585 deliveries were in Ilsan Paik Hospital. We selected 70 (epidural group) and 87 (non-epidural group) singleton, nulliparous, term, cephalic presentation without antenatal complications. We compared duration of labor, rates of Cesarean delivery and perinatal outcomes between these two groups. RESULTS: The duration of active and second stage of labor were not prolonged in the epidural group. Cesarean delivery rates was 8.6% (n=70) in the epidural group and 9.2% (n=87) in the non-epidural group, so there was no significant difference. Perinatal outcomes was no significant difference between the two groups. CONCLUSION: Epidural anesthesia during labor provides the best pain relief and does not increase the Cesarean delivery rates. The duration of the active, second stage of labor and perinatal outcomes was not different between these two groups.
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Anestesia EpiduralRESUMEN
Recently, in Korea, imported malarial infections are increased and occasionally domestic infections are reported. But the malarial infected pregnant women are seldom cases and we have experienced second trimester infected one. She had no traveling and transfusion history. She delivered a healthy baby at term by repeated cesarean section and her baby had no evidence of congenital malarial infection. We treated her with hydroxychloroquine at antepartum and primaquine at postpartum. We present this case with a brief review of literatures.
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Femenino , Humanos , Embarazo , Cesárea , Hidroxicloroquina , Corea (Geográfico) , Malaria , Periodo Posparto , Segundo Trimestre del Embarazo , Mujeres Embarazadas , PrimaquinaRESUMEN
OBJECTIVE: To evaluate the efficacy of color Doppler ultrasound in diagnosis and management of placenta previa with accreta. METHODS: Hospital records were reviewed all cases of placenta previa from December 1999 to June 2002, and seventy-four patients with placenta previa underwent color Doppler ultrasound in their second and third trimester. Four diagnostic criteria of placenta accreta were diffuse lacunar flow pattern, exhibiting diffusely dilated vascular channels throughout the whole placenta: focal lacunar flow pattern showing irregular sonolucent vascular lakes, regionally or focally within the intraparenchymal placental area: absence of subplacental vascular signals in the areas lacking the peripheral subplacental hypoechoic zone: interphase hypervascularity with abnormal blood vessels linking the placenta to the bladder. RESULTS: Twenty-four of the seventy-four patients diagnosed placenta previa with accreta according to the above criteria and thirteen of these have proven to placenta accreta histopathologically. In ten cases hysterectomy were done under the group of suspicious placenta accreta. The sensitivity, specificity, positive predictive value and negative predictive value were 100%, 83%, 56% and 100%. CONCLUSION: The color Doppler ultrasound was effective method for the diagnosis of placenta previa with accreta, so proper diagnosis will be helpful to management of placenta previa with accreta patients.
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Femenino , Humanos , Embarazo , Vasos Sanguíneos , Diagnóstico , Registros de Hospitales , Histerectomía , Interfase , Lagos , Placenta Accreta , Placenta Previa , Placenta , Tercer Trimestre del Embarazo , Sensibilidad y Especificidad , Ultrasonografía , Vejiga UrinariaRESUMEN
No abstract available.