RESUMEN
OBJECTIVES: Against the background of a possibly compromised functional adaptation, the relationship between the height of the articular tubercle was analyzed as a function of the amount of divergence between the maxilla and the mandible. DESIGN: These parameters were obtained retrospectively from orthopantomograms and lateral radiographs produced in a standard procedure before orthodontic treatment. RESULTS: The height of the articular tubercle appeared to be significantly smaller in a group of patients with a dolichofacial morphology, with respect of those with an average (mesofacial) morphology. Furthermore, there was a significant correlation between the height of the articular tubercle and the mandibular angle. CONCLUSIONS: These results suggest that bone remodeling in selected parts of the orofacial skeleton can be compromised giving rise to an altered craniofacial morphology.
Asunto(s)
Anomalías Craneofaciales/fisiopatología , Desarrollo Maxilofacial , Ortodoncia Correctiva , Articulación Temporomandibular/anomalías , Fenómenos Biomecánicos , Remodelación Ósea/fisiología , Cefalometría , Anomalías Craneofaciales/diagnóstico por imagen , Femenino , Humanos , Masculino , Radiografía Panorámica , Estudios Retrospectivos , Articulación Temporomandibular/diagnóstico por imagenRESUMEN
OBJECTIVE: Routine electrophysiological testing is often normal in the evaluation of painful diabetic neuropathy, as it is unable to detect dysfunction of thinly myelinated (Aδ) and unmyelinated (C) small fibers. Although cutaneous silent periods (CSP) and quantitative sudomotor axon reflex testing (QSART) respectively evaluate these fiber types in the extremities, these two tests have yet to be assessed together. METHODS: 26 patients with a clinical diagnosis of small fiber neuropathy (SFN) and 26 age-matched controls were assessed. Nine patients had Type I diabetes, nine had Type II diabetes, and eight had impaired glucose tolerance. The CSP onset latency and duration were recorded in each extremity. QSART was performed on the right side. RESULTS: 58% (15/26) of patients had abnormal sweat volumes obtained from QSART, while 50% (13/26) of patients had abnormal CSP responses. Combining these two tests increased the sensitivity of testing to 77% (20/26). Abnormalities were seen equally across all patient groups. CONCLUSIONS: Combining CSP with QSART significantly increases the sensitivity of testing when assessing patients with SFN related to diabetes, or prediabetes. SIGNIFICANCE: For clinically suspected SFN, it is preferable to test more than one small fiber type, as each possess different structural and functional properties and may be heterogeneously affected between patients.
Asunto(s)
Neuropatías Diabéticas/fisiopatología , Eritromelalgia/fisiopatología , Reflejo , Piel/inervación , Adulto , Anciano , Axones/fisiología , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Conducción NerviosaRESUMEN
A lot of studies published on the ten last years showed a decrease of fertility among HIV positive women. The present research aims to see if this decrease is linked to an ovarian failure, using AMH as principal marker of ovarian function. In this pilot study, 54 HIV-positive and 39 HIV-negative women were compared on the basis of their ovarian function, fecundity and possible ovarian failure. A blood sample was taken for hormonal titrations, HIV seropositivity, viral load and CD4 T cell count. An interview explored demographic characteristics, obstetrical and infectious history, and menstrual characteristics. This study was performed in Burkina Faso between January and February 2008. There is no significant difference after adjusting for age of AMH level between the two groups. However, in our study, 5.5% of HIV positive women had a premature menopause, which is a significant variation from the premature menopause rates of the African population, which is 1.4%. In conclusion, this study put the HIV impact on ovarian function into perspective but the high premature menopause rates could suggest an ovarian attack by the virus or the treatment.
Asunto(s)
Infecciones por VIH/epidemiología , Infecciones por VIH/fisiopatología , Enfermedades del Ovario/epidemiología , Ovario/fisiopatología , Adolescente , Adulto , Antirretrovirales/uso terapéutico , Burkina Faso/epidemiología , Estudios de Casos y Controles , Femenino , Infecciones por VIH/sangre , Infecciones por VIH/tratamiento farmacológico , Seropositividad para VIH , VIH-1 , Hormonas/sangre , Humanos , Persona de Mediana Edad , Enfermedades del Ovario/sangre , Proyectos Piloto , Adulto JovenRESUMEN
Density maps show trends in objects' trajectories. Density map creation involves aggregating smoothed trajectories in a density field and visualizing the field. Using an interactive distribution map, users can define subsets and, supported by graphics hardware, get fast feedback for these computationally expensive density field calculations.