RESUMEN

We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 +/- 1.7 (+/-SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 +/- 1.1 years; n = 759).

Asunto(s)

Pubertad Precoz/etiología , Síndrome de Williams/complicaciones , Adolescente , Distribución por Edad , Estudios de Casos y Controles , Niño , Femenino , Alemania/epidemiología , Humanos , Prevalencia , Pubertad Precoz/epidemiología , Estadísticas no Paramétricas