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Objective To study the helicobacter pylori(HP)infection and incidence of motion sickness,and observe the improment of motion sickness symptoms of motion sickness group after eradication of helicobacter pylori. Methods Random drawing from chronic gastritis of digestive diseases outpatient spot in the crowd of 765 people, which were investigated through the age,job title,medical history,symptoms of motion sickness and 14 C -UBT test. 153 cases of motion sickness with 14 C -UBT test positive were observed before and after helicobacter pylori eradication of the change of motion sickness symptoms by using quadruple therapy in patients with helicobacter pylori eradication, results were analyzed according to the survey.Results 765 people,384 cases HP positive,HP total positive rate 50.20%.motion sickness occurred in 213 cases,motion sickness was 153 cases HP positive,HP positive rate 71.83%(153 /213);Without HP positive,231 cases of motion sickness,positive rate of motion sickness group were 41.85%(231 /552),which were similar between the two groups with statistically significant(χ2 =55.27,P <0.05). In the HP positive and carsick 153 cases,76 cases of using quadruple therapy for the eradication of helicobacter pylori,and motion sickness symptoms improved were 11 cases 1 years later.The eradication of helicobacter pylori was not used in 77 cases,in which motion sickness symptoms improved for 2 cases 1 year later.And the comparative difference was statistically significant(χ2 =6.94,P <0.05).Conclusion HP infection has certain correlation with the incidence of motion sickness,the eradication of helicobacter pylori may be beneficial to improve the symptoms of motion sickness.
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Objective To explore the combined detection of serum osteopontin(OPN),gastric cancer associ-ated antigen(MG7 -Ag)and tissue polypeptide specific antigen(TPS)for the clinical value of diagnosis of gastric cancer.Methods Enzyme linked immunosorbent test(ELISA)was used to detect serum levels of OPN,MG7 -Ag and TPS of 60 cases of gastric cancer patients,gastric benign lesion group 20 cases were randomly selected at the same time,the group of 24 cases of precancerous lesions and 40 healthy people were also selected as control study.Results Gastric cancer group′s serum levels of OPN,MG7 -Ag and TPS were significantly higher than those of gastric benign lesions,the precancerous lesion group and healthy control group(F =50.993,62.50,41.396,all P <0.01 ).The single detection sensitivity were 71.7%,80.0% and 67.3% respectively,three joint detection sensitivity was 91.7%.Conclusion Combined detection of serum OPN,MG7 -Ag and TPS can improve the sensitivity of diagnosis of gastric cancer,and has higher diagnosis significance in the diagnosis of gastric cancer.
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Objective To study the effect of endoscopic treatment for acute appendicitis (AA)without perforation or gangrene.Methods A total of 94 patients with AA were randomly divided into operation group (n =45 ) to receive appendectomy,control group (n =15 ) to accept conventional medicine of metronidazole and Cefoxitin and colonoscopy group (n =34) to undergo conventional medicine plus endoscopic treatment.The time for alleviation of abdominal pain,duration and mean cost of the hospitalization,and the recurrence rate in one year were compared.Results Compared to operation group,colonoscopy group was superior in the duration [ (2.77 ± 0.27) d vs.(6.65 ± 1.68) d ] and mean cost of hospitalization [ ( 1011.35 ± 22.12) yuan vs.(4023.37 ± 32.02 ) yuan ] ( P ＜ 0.05 and P ＜ 0.01,respectively).There were no significant differences in the time for alleviation of abdominal pain or the recurrence rate in one year between 2 groups.Colonoscopy group was superior to control group in all the indices (P ＜ 0.05 ).Conclusion Endoscopic treatment for AA without perforation and gangrene is effective and safe,which can be considered as the first-line treatment.
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Objective To study the clinical value of serum SA,EMA and GPDA in the diagnosis of gastric cancer.Methods To detect serum SA,EMA and GPDA in 30 patients with gastric cancer patients,25 patients with gastric precancerous lesions and 35 patients with non-atrophic gastritis with electronic gastroscope and pathological examination confirmed,compared the differences betwwen the groups,and analyze the relationship between the expressions of them and clinical biology of gastric carcinoma.Results The serum concentrations of SA and GPDA in gastric carcinoma are remarkably higher than those in non-atrophic gastritis and gastric precancerous lesions(P0.05).The concentrations of GPDA in non-atrophic gastritis group are age-related(P0.05).Conclusion It has an important reference value for the diagnosis of gastric cancer to detect serum SA and GPDA.SA and GPDA together can improve the accuracy of the diagnosis of gastric cancer.EMA serum possibly has no diagnostic value for gastric cancer.The expressions of SA,GPDA in serum are related to the biology behaviors of gastric carcinoma,and the concentrations of SA,GPDA in serum is helpful in judging metastasis and recrudescence,and monitoring prognosis.