Asunto(s)
Aneurisma/complicaciones , Enfermedades del Conducto Colédoco/complicaciones , Quistes/complicaciones , Hemobilia/etiología , Arteria Hepática , Aneurisma/diagnóstico por imagen , Colangiografía , Enfermedades del Conducto Colédoco/diagnóstico por imagen , Quistes/diagnóstico por imagen , Femenino , Arteria Hepática/diagnóstico por imagen , Humanos , LactanteRESUMEN
To determine effects of wholesale and retail contamination on steak retail case life, rib steaks were fabricated from wholesale beef ribs using laboratory-simulated extremes of retail processing sanitation. Steak retail case life was more highly correlated with the psychrotrophic bacterial load on the surface of wholesale ribs and retail steaks than with the level of retail processing sanitation. Although steak case life could be predicted as a function of both steak and rib bacterial loads or rib and retail equipment bacterial loads the, following is recommended as the most useful predictor of case life: Steak Case Life (days) = 3.97 - 0.19 (log bacteria/cm2 on wholesale ribs) -0.14 (log bacteria/cm2 on retail processing equipment). This equation could also be used by the retailer to assess the quality of wholesale product received from different suppliers.
RESUMEN
A 22-year-old man was seen with Addison's disease, psychosis, and neurologic abnormalities. A tentative diagnosis of adrenoleukomyeloneuropathy was made. Because of his age, negative family history, and the potentially serious prognosis of this disorder, the diagnosis was verified with an adrenal biopsy. We believe this procedure is the method of choice in confirming the sporadic, atypical case of adrenoleukomyeloneuropathy.
Asunto(s)
Enfermedades de las Glándulas Suprarrenales/diagnóstico , Glándulas Suprarrenales/patología , Esclerosis Cerebral Difusa de Schilder/diagnóstico , Enfermedades del Sistema Nervioso/diagnóstico , Enfermedades de la Médula Espinal/diagnóstico , Enfermedad de Addison/etiología , Adulto , Biopsia , Encefalopatías/diagnóstico por imagen , Diagnóstico Diferencial , Humanos , Masculino , Trastornos Psicóticos/etiología , Radiografía , Convulsiones/etiología , Síndrome , Terminología como AsuntoRESUMEN
Mice allowed to exercise during the late postnatal period had Purkinje cells with larger dendritic trees and greater numbers of spines than littermates whose physical activity was severly restricted. These changes in Purkinje cells were accompanied by a selective reduction in the thickness of the cerebellar molecular layer. The data provide evidence for cerebellar plasticity during late development and demonstrate that physical activity can modify the development of Purkinje cell dendrites.
Asunto(s)
Cerebelo/crecimiento & desarrollo , Células de Purkinje/citología , Animales , Conducta Animal/fisiología , Diferenciación Celular , Corteza Cerebelosa/crecimiento & desarrollo , Dendritas/ultraestructura , Femenino , Masculino , Ratones , Actividad Motora/fisiología , Esfuerzo FísicoRESUMEN
The late postnatal development of the Purkinje cell dendritic tree in mouse cerebellar vermis was investigated in Golgi preparations by morphometric techniques in order to determine at what age adult characteristics of the Purkinje cell are achieved in the rodent brain which grows continuously throughout adult life. B6D2F1 hybrid mice were sacrificed at 9, 15, 20, 35 and 250 days of age. "Hind-brain" weights (by direct weighing) and vermis volume (determined histometrically from Golgi sections), both increased rapidly from 9 to 20 days of age and continued to increase steadily with advancing age. The growth of Purkinje dendritic field areas, determined by planimetric measurements from Golgi sections paralleled the growth curves for vermis cross-sectional area, vermis volume and "hindbrain" weight. However, stereological determinations revealed an unexpected disparity between the growth of the Purkinje dendritic field areas and changes in the total length of dendrites of Purkinje cells. The total dendritic branch length per Purkinje cell increased sharply up to 20 days of age but thereafter declined with advancing age. Dendritic spine counts on Purkinje cells revealed no change in the number of dendritic spines per unit length of dendrites between 20 and 250 days of age, however, since the Purkinje cell total branch length declined-calculations suggest that the total number of spines per cell declined after 20 days of age. Thus, the size of the cerebellum and the Purkinje cell dendritic tree continued to enlarge during late postnatal development; however, the total dendritic surface area and the total number of dendritic spines on each Purkinje cell, after reaching a peak at 20 days of age, declined with advancing age. The data suggest that the late postnatal development of the Purkinje cell dendritic tree is characterized by resorption as well as dendritic growth. The functional significance of such developmental remodelling is unknown.