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1.
Nature ; 601(7893): 320-322, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-35046596
2.
Phys Rev E ; 99(5-1): 052407, 2019 May.
Artículo en Inglés | MEDLINE | ID: mdl-31212542

RESUMEN

The statistical analysis of the collective neural activity known as avalanches provides insight into the proper behavior of brains across many species. We consider a neural network model based on the work of Lombardi, Herrmann, De Arcangelis et al. that captures the relevant dynamics of neural avalanches, and we show how tuning the fraction of inhibitory neurons in this model alters the connectivity of the network over time, removes exponential cut-offs present in the distributions of avalanche size and duration, and transitions the power spectral density of the network into an "epileptic" regime. We propose that the brain operates away from this power-law regime of low inhibitory fraction to protect itself from the dominating avalanches present in these extended distributions. We present control strategies that curtail these power-law distributions through either random or, more effectively, targeted disabling of excitatory neurons.

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