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BACKGROUND AND OBJECTIVE: The accurate diagnosis of schizophrenia spectrum disorder plays an important role in improving patient outcomes, enabling timely interventions, and optimizing treatment plans. Functional connectivity analysis, utilizing functional magnetic resonance imaging data, has been demonstrated to offer invaluable biomarkers conducive to clinical diagnosis. However, previous studies mainly focus on traditional machine learning methods or hand-crafted neural networks, which may not fully capture the spatial topological relationship between brain regions. METHODS: This paper proposes an evolutionary algorithm (EA) based graph neural architecture search (GNAS) method. EA-GNAS has the ability to search for high-performance graph neural networks for schizophrenia spectrum disorder prediction. Moreover, we adopt GNNExplainer to investigate the explainability of the acquired architectures, ensuring that the model's predictions are both accurate and comprehensible. RESULTS: The results suggest that the graph neural network model, derived using genetic algorithm search, outperforms under five-fold cross-validation, achieving a fitness of 0.1850. Relative to conventional machine learning and other deep learning approaches, the proposed method yields superior accuracy, F1 score, and AUC values of 0.8246, 0.8438, and 0.8258, respectively. CONCLUSION: Based on a multi-site dataset from schizophrenia spectrum disorder patients, the findings reveal an enhancement over prior methods, advancing our comprehension of brain function and potentially offering a biomarker for diagnosing schizophrenia spectrum disorder.

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Accurate finger gesture recognition with surface electromyography (sEMG) is essential and long-challenge in the muscle-computer interface, and many high-performance deep learning models have been developed to predict gestures. For these models, problem-specific tuning of network architecture is essential for improving the performance, yet it requires substantial knowledge of network architecture design and commitment of time and effort. This process thus imposes a major obstacle to the widespread and flexible application of modern deep learning. To address this issue, we present an auto-learning search framework (ALSF) to generate the integrated block-wised neural network (IBWNN) for sEMG-based gesture recognition. IBWNN contains several feature extraction blocks and dimensional reduction layers, and each feature extraction block integrates two sub-blocks (i.e., multi-branch convolutional block and triplet attention block). Meanwhile, ALSF generates optimal models for gesture recognition through the reinforcement learning method. The results show that the generated models yield state-of-the-art results compared to the modern popular networks on the open dataset Ninapro DB5. Moreover, compared to other networks, the generated models have fewer parameters and can be deployed in practical applications with less resource consumption.

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Muscle fatigue detection is of great significance to human physiological activities, but many complex factors increase the difficulty of this task. In this article, we integrate several effective techniques to distinguish muscle states under fatigue and nonfatigue conditions via surface electromyography (sEMG) signals. First, we perform an isometric contraction experiment of biceps brachii to collect sEMG signals. Second, we propose a neural architecture search (NAS) framework based on reinforcement learning to autogenerate neural networks. Finally, we present an effective two-step training strategy to improve the performance by combining CNN with three types of commonly used statistical algorithms. Meanwhile, we propose a data enhancement algorithm based on empirical mode decomposition (EMD) to generate time-series data for expanding the dataset. The results show that this search algorithm can hunt for high-performing networks, and the accuracy of the best-selected model combined with support vector machine (SVM) for the group is 96.5%. With the same architecture, the average accuracy in individual models is 97.8%. The proposed data enhancement technique can effectively improve the fatigue detection performance, which allows further implementations in the human-exoskeleton interaction systems.

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Intention recognition based on surface electromyography (sEMG) signals is pivotal in human-machine interaction (HMI), where continuous motion estimation with high accuracy has been the challenge. The convolutional neural network (CNN) possesses excellent feature extraction capability. Still, it is difficult for ordinary CNN to explore the dependencies of time-series data, so most researchers adopt the recurrent neural network or its variants (e.g., LSTM) for motion estimation tasks. This paper proposes a multi-feature temporal convolutional attention-based network (MFTCAN) to recognize joint angles continuously. First, we recruited ten subjects to accomplish the signal acquisition experiments in different motion patterns. Then, we developed a joint training mechanism that integrates MFTCAN with commonly used statistical algorithms, and the integrated architectures were named MFTCAN-KNR, MFTCAN-SVR and MFTCAN-LR. Last, we utilized two performance indicators (RMSE and [Formula: see text]) to evaluate the effect of different methods. Moreover, we further validated the performance of the proposed method on the open dataset (Ninapro DB2). When evaluating on the original dataset, the average RMSE of the estimations obtained by MFTCAN-KNR is 0.14, which is significantly less than the results obtained by LSTM (0.20) and BP (0.21). The average [Formula: see text] of the estimations obtained by MFTCAN-KNR is 0.87, indicating the anti-disturbance ability of the architecture. Moreover, MFTCAN-KNR also achieves high performance when evaluating on the open dataset. The proposed methods can effectively accomplish the task of motion estimation, allowing further implementations in the human-exoskeleton interaction systems.

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