RESUMEN
The authors conducted a 10-year retrospective review of all patients within one physician's practice to determine the frequency of spontaneous resolution of congenital nasolacrimal duct obstruction in children older than 1 year during the interval between scheduling and date of probing. This review found 4.4% of eyes resolved within an average interval period of 39 days. [J Pediatr Ophthalmol Strabismus. 2019;56:e31-e33.].
Asunto(s)
Dacriocistorrinostomía , Obstrucción del Conducto Lagrimal/congénito , Conducto Nasolagrimal/anomalías , Femenino , Estudios de Seguimiento , Humanos , Lactante , Masculino , Conducto Nasolagrimal/diagnóstico por imagen , Remisión Espontánea , Estudios RetrospectivosRESUMEN
PURPOSE: To describe features of atypical pleomorphic adenoma, a rare clinical entity, particularly when found in ectopic periocular lacrimal gland tissue. METHODS: Case report of biopsy-confirmed periocular atypical pleomorphic adenoma. RESULTS: A 35-year-old female presented with a unique orbital lesion found to be ectopic lacrimal gland demonstrating atypical pleomorphic adenoma on formal histopathologic review. Pleomorphic adenoma is pathologically characterized as an epithelial lesion intermixed with mesenchymal elements. It is further classified as atypical with the presence of features such as hypercellularity, regions of necrosis or hyalinization, cellular dysplasia, capsular violation, and malignant characteristics without frank local extension or distant metastases. CONCLUSIONS: Due to its rarity, the natural history and prognosis of atypical pleomorphic adenoma is unclear. Physicians need to recognize this entity, and complete surgical excision with strict follow-up regimens are likely warranted.
Asunto(s)
Adenoma Pleomórfico/diagnóstico , Neoplasias del Ojo/diagnóstico , Aparato Lagrimal/anomalías , Adulto , Biopsia , Diagnóstico Diferencial , Femenino , Humanos , Aparato Lagrimal/patología , Enfermedades del Aparato Lagrimal/cirugía , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND: Paranasal sinus lymphoma is a rare clinical entity. METHODS: We conducted a retrospective case series of 68 patients with biopsy-confirmed paranasal sinus lymphoma with attention on systemic disease association. RESULTS: Of 63 patients with paranasal sinus lymphoma, 35 (56%) had systemic involvement. Four patient groups were identified: (1) primary paranasal sinus lymphoma (44%); (2) systemic disease occurring concurrently with paranasal sinus lymphoma (25%); (3) paranasal sinus lymphoma with relapse of preexisting systemic lymphoma (22%); and (4) progression to systemic disease after primary paranasal sinus lymphoma (8%). Most of the patients with systemic disease were diagnosed at 50 + years and had positive smoking histories. There was a trend toward disease activity in the neighboring ocular location. For patients with preexisting systemic lymphoma, the mean time to paranasal sinus lymphoma was 65 months. When systemic lymphoma developed after localized paranasal sinus lymphoma, mean time to progression was 23 months. Diffuse large B cell lymphoma was the most common paranasal sinus lymphoma. CONCLUSION: There is a risk of systemic involvement during the disease course of paranasal sinus lymphoma. Biopsy is the preferred first management step and should precede debulking or mass resection in nonemergent cases. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1065-1070, 2017.
Asunto(s)
Tratamiento Conservador , Linfoma de Células B Grandes Difuso/epidemiología , Linfoma de Células B Grandes Difuso/patología , Neoplasias de los Senos Paranasales/epidemiología , Neoplasias de los Senos Paranasales/patología , Adulto , Distribución por Edad , Anciano , Anciano de 80 o más Años , Estudios de Cohortes , Terapia Combinada , Femenino , Humanos , Inmunohistoquímica , Incidencia , Linfoma de Células B Grandes Difuso/terapia , Masculino , Persona de Mediana Edad , Invasividad Neoplásica/patología , Estadificación de Neoplasias , Neoplasias de los Senos Paranasales/terapia , Pronóstico , Enfermedades Raras , Estudios Retrospectivos , Medición de Riesgo , Distribución por Sexo , Tasa de Supervivencia , Adulto JovenRESUMEN
Orbital Hodgkin lymphoma is infrequent, representing less than 1% of adult orbital malignancies. It is typically seen in the setting of terminally advanced systemic disease. This case highlights orbital, head, and neck disease in a systemically stable individual treated with the novel anti-CD30 monoclonal antibody brentuximab vedotin.
Asunto(s)
Enfermedad de Hodgkin/tratamiento farmacológico , Inmunoconjugados/uso terapéutico , Neoplasias Orbitales/tratamiento farmacológico , Adulto , Biomarcadores de Tumor/metabolismo , Brentuximab Vedotina , Enfermedad de Hodgkin/diagnóstico , Enfermedad de Hodgkin/metabolismo , Humanos , Imagen por Resonancia Magnética , Masculino , Neoplasias Orbitales/diagnóstico , Neoplasias Orbitales/metabolismoRESUMEN
PURPOSE: To identify barriers to ophthalmological follow-up in high-risk children who are identified by vision screening and eye examination. METHODS: The records of patients identified as needing follow-up through two free eye care programs (organized optometric and ophthalmologic screening sessions aimed at identifying and treating ocular pathology) targeted toward inner-city youths of low socioeconomic status were reviewed. Parents were contacted by phone, and a questionnaire on barriers to follow-up was administered. Callers attempted to schedule appointments at that time. Data were assessed by means of descriptive analysis. RESULTS: Of 93 patients, 54 (58%), were successfully contacted. Of these, 23 (25%) were eventually scheduled. Five (5%) patients elected follow-up elsewhere. Twenty (22%) with working phones were still unable to be scheduled. Additional obstacles included families' lack of awareness of the need for follow-up (13%), assumption by families that they would be contacted (5%), scheduling conflicts (4%), concerns about insurance, and difficulty finalizing referrals (2%). A total of 39 patients (42%) were not successfully contacted because of inoperable phone services, and none of the families responded to the mailed questionnaire. CONCLUSIONS: Inability to contact families was the greatest barrier to follow-up. Our findings suggest that immediate arrangement of follow-up care, on-site visual assessment, and a program director may be useful in increasing follow-up for high-risk children.