RESUMEN
Cardiodynamics and myocardial contractile reserve were studied in 60 patients with hypertrophic cardiomyopathy by using radionuclide ventriculography at rest and during graded exercise test. All findings that characterize cardiodynamics (normal or higher overall ejection fraction and stroke volume or lower end-systolic volume, higher maximum ejection rate) show the contractility of the left ventricle in patients with hypertrophic cardiomyopathy which can be regarded to be more severe. During graded exercise test, in patients with hypertrophic cardiomyopathy three types of reactions were identified: (1) positive inotropic effect; (2) negative inotropic effect; (3) intermediate (deviation of major cardiodynamic parameters was no more than 20-25% of the baseline levels). Identification of the above types allows one to assess the presence and conditions of myocardial contractile reserve implementation in these patients and to objectivize the choice of corrective drugs.
Asunto(s)
Cardiomiopatía Hipertrófica/fisiopatología , Corazón/fisiopatología , Contracción Miocárdica , Adolescente , Adulto , Cardiomiopatía Hipertrófica/diagnóstico , Ecocardiografía , Prueba de Esfuerzo , Imagen de Acumulación Sanguínea de Compuerta , Hemodinámica , Humanos , Persona de Mediana EdadRESUMEN
The features of diastolic filling of the left ventricle (LV) were examined in relation to the nature of its hypertrophy in patients with coronary heart disease (CHD). A total of 110 male patients with CHD concurrent with essential hypertension or without it who underwent contrast ventriculography in order to determine LV diastolic stiffness. Radionuclide ventriculography was performed in 49 patients at rest and during exercise. The CHD patients with moderate LV concentric hypertrophy had more adequate LV diastolic filling in the presence of concurrent essential hypertension. Abnormal diastolic filling was more pronounced in CHD patients without hypertrophy or its eccentric development than in those without essential hypertension.
Asunto(s)
Cardiomegalia/fisiopatología , Enfermedad Coronaria/fisiopatología , Diástole/fisiología , Hemodinámica/fisiología , Función Ventricular Izquierda/fisiología , Adulto , Cardiomegalia/diagnóstico por imagen , Cardiomegalia/etiología , Enfermedad Coronaria/complicaciones , Enfermedad Coronaria/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Ventriculografía con Radionúclidos , Índice de Severidad de la Enfermedad , Pertecnetato de Sodio Tc 99mAsunto(s)
Cardiomiopatía Hipertrófica/fisiopatología , Diástole , Función Ventricular Izquierda , Adolescente , Adulto , Cardiomiopatía Hipertrófica/diagnóstico , Ecocardiografía , Electrocardiografía , Imagen de Acumulación Sanguínea de Compuerta , Ventrículos Cardíacos/diagnóstico por imagen , Humanos , Persona de Mediana Edad , Pertecnetato de Sodio Tc 99mAsunto(s)
Enfermedades Cardiovasculares/radioterapia , Microondas/uso terapéutico , Adulto , Cardiomiopatía Hipertrófica/fisiopatología , Cardiomiopatía Hipertrófica/radioterapia , Enfermedades Cardiovasculares/fisiopatología , Enfermedad Coronaria/fisiopatología , Enfermedad Coronaria/radioterapia , Estudios de Evaluación como Asunto , Hemodinámica/efectos de la radiación , Humanos , Masculino , Persona de Mediana Edad , Resistencia Física/efectos de la radiaciónRESUMEN
An analysis of the dynamics of diastolic rigidity, contractile function of the left ventricle and physical load tolerance under the effect of single intakes of phynoptin and corinfar and their course use in patients with IHD showed that they were more effective in case of increased mass of the myocardium. This indicates that increased mass of the myocardium is an additional indication to calcium antagonists in these patients.
Asunto(s)
Bloqueadores de los Canales de Calcio/uso terapéutico , Cardiomegalia/tratamiento farmacológico , Enfermedad Coronaria/tratamiento farmacológico , Adulto , Cardiomegalia/etiología , Cardiomegalia/fisiopatología , Enfermedad Coronaria/complicaciones , Enfermedad Coronaria/fisiopatología , Evaluación de Medicamentos , Hemodinámica/efectos de los fármacos , Humanos , Masculino , Persona de Mediana Edad , Nifedipino/administración & dosificación , Verapamilo/administración & dosificaciónAsunto(s)
Cardiomegalia/fisiopatología , Enfermedad Coronaria/fisiopatología , Resistencia Física/fisiología , Esfuerzo Físico/fisiología , Función Ventricular Izquierda/fisiología , Adulto , Cardiomegalia/diagnóstico , Angiografía Coronaria , Enfermedad Coronaria/diagnóstico , Electrocardiografía , Prueba de Esfuerzo , Ventrículos Cardíacos/diagnóstico por imagen , Humanos , Hipertensión/diagnóstico , Hipertensión/fisiopatología , Masculino , Persona de Mediana Edad , Infarto del Miocardio/diagnóstico , Infarto del Miocardio/fisiopatologíaRESUMEN
A relationship was examined between the development of myocardial ischemia in patients with coronary heart disease before coronary ventriculography and the status of coronary vessels, coronary reserve, myocardial contractility, and the autonomic nervous system. Before coronary ventriculography, myocardial ischemia was found to occur in the patients when there was a marked activation in the sympathetic portion of the autonomic nervous system and a clear-cut decrease in coronary reserve. The occurrence of myocardial ischemia in the patients before coronary ventriculography contributed to decreased left ventricular myocardial contractility and increased the cardiodepressive effects of a contrast agent.
Asunto(s)
Angiografía , Angiografía Coronaria , Enfermedad Coronaria/diagnóstico , Ventrículos Cardíacos/diagnóstico por imagen , Adulto , Enfermedad Coronaria/diagnóstico por imagen , Enfermedad Coronaria/fisiopatología , Electrocardiografía , Prueba de Esfuerzo , Humanos , Masculino , Persona de Mediana Edad , Contracción MiocárdicaRESUMEN
It was established that left ventricular hypertrophy in patients with ischemic heart disease associated with hypertensive disease reflects a functionally more intact myocardium than similar hypertrophy in analogous patients without hypertensive disease. Hypertrophy of the left ventricle in patients with ischemic heart of different severity may be considered an index of myocardial lesion and this should be considered in the treatment tactics.
Asunto(s)
Cardiomegalia/fisiopatología , Enfermedad Coronaria/fisiopatología , Función Ventricular Izquierda/fisiología , Adulto , Cardiomegalia/diagnóstico , Cardiomegalia/etiología , Enfermedad Coronaria/complicaciones , Enfermedad Coronaria/diagnóstico , Hemodinámica/fisiología , Humanos , Hipertensión/complicaciones , Hipertensión/diagnóstico , Hipertensión/fisiopatología , Masculino , Persona de Mediana EdadRESUMEN
The authors compared the electrical activity of the heart with results of echocardiography during rest and during bicycle ergometry [correction of veloergometry] in 240 patients with ischemic heart disease, 60 patients with hypertensive disease and in 16 healthy persons. In some of the patients coronarography was carried out. It was established that the informative value of electrocardiography in assessment of the anatomo-functional state of the left ventricle depended on the contingent of the examined patients and reduces as disorders of the functional state of the myocardium tended to advance. The specificity and sensitivity of the electrocardiographic signs of left ventricular hypertrophy reduced in disturbances of ventricular conduction, presence of myocardial infarction in the anamnesis, increase of involvement of the cardiac arteries.
Asunto(s)
Cardiomegalia/diagnóstico , Electrocardiografía , Adulto , Cardiomegalia/etiología , Angiografía Coronaria , Enfermedad Coronaria/complicaciones , Enfermedad Coronaria/diagnóstico , Ecocardiografía , Estudios de Evaluación como Asunto , Humanos , Hipertensión/complicaciones , Hipertensión/diagnóstico , Masculino , Persona de Mediana EdadRESUMEN
Assessment of myocardial contractility function and its diastolic features (according to the results of radionuclide ventriculography with 99mTc-pertechnetate) in patients with dilatory cardiomyopathy (DCMP) revealed a significant decrease in the total ejection fraction, regional ejection fractions, cardiomegaly (an increase in the end-diastolic volume combined with an increase in end-systolic volume and a decrease in the stroke volume) and a decrease in ejection rate indices. Differential criteria for the diagnosis of DCMP and CHD were a greater degree of cardiodynamic indices and a diffuse decrease in myocardial regional contractility function in the former and heterogeneity of changes in regional contractility in the latter pathology. The process of diastolic filling in DCMP patients was characterized by a marked decrease in a filling rate at reduced time of its achievement, and in CHD patients by a decrease in a maximum filling rate in combination with increased time of its achievement.
Asunto(s)
Cardiomiopatía Dilatada/diagnóstico por imagen , Ventriculografía con Radionúclidos , Adulto , Cardiomiopatía Dilatada/fisiopatología , Enfermedad Coronaria/diagnóstico por imagen , Enfermedad Coronaria/fisiopatología , Diagnóstico Diferencial , Difosfatos , Humanos , Masculino , Persona de Mediana Edad , Contracción Miocárdica/fisiología , Infarto del Miocardio/diagnóstico por imagen , Infarto del Miocardio/fisiopatología , Ventriculografía con Radionúclidos/métodos , Pertecnetato de Sodio Tc 99m , Tecnecio , Pirofosfato de Tecnecio Tc 99mRESUMEN
Differential evaluation was carried out of hypertrophy as a factor possibly of compensatory or that of furthering disturbances of the coronary circulation and contractile function of the myocardium. Echocardiography, radionuclide ventriculography tests with physical loads revealed that only moderate hypertrophy of the left ventricle in IHD patients with hypertensive disease (grade II) may be considered as one of the compensatory factors maintaining the functional state of the left ventricle myocardium.
Asunto(s)
Enfermedad Coronaria/fisiopatología , Hipertensión/fisiopatología , Contracción Miocárdica , Cardiomegalia/diagnóstico , Cardiomegalia/fisiopatología , Enfermedad Coronaria/diagnóstico , Ecocardiografía , Prueba de Esfuerzo , Ventrículos Cardíacos/diagnóstico por imagen , Ventrículos Cardíacos/fisiopatología , Hemodinámica , Humanos , Hipertensión/diagnóstico , Cintigrafía , Pertecnetato de Sodio Tc 99mAsunto(s)
Enfermedad Coronaria/diagnóstico , Vasos Coronarios/fisiopatología , Adulto , Angiografía Coronaria , Enfermedad Coronaria/fisiopatología , Vasos Coronarios/patología , Ecocardiografía , Electrocardiografía , Prueba de Esfuerzo , Hemodinámica , Humanos , Masculino , Persona de Mediana Edad , Modelos Cardiovasculares , Pletismografía de ImpedanciaRESUMEN
A study of the effects of exercise on cardiovascular function of myocardial infarction survivors showed their physical stress tolerance to increase as a result of improved myocardial contractility and the optimum adjustment of hemodynamic and oxygen support of exercise. Therefore, exercise should be used more extensively as part of the rehabilitation effort following myocardial infarction.
Asunto(s)
Terapia por Ejercicio , Infarto del Miocardio/rehabilitación , Adulto , Electrocardiografía , Hemodinámica , Humanos , Masculino , Persona de Mediana Edad , Infarto del Miocardio/fisiopatología , Resistencia FísicaAsunto(s)
Hemodinámica , Infarto del Miocardio/fisiopatología , Adulto , Prueba de Esfuerzo , Ventrículos Cardíacos/diagnóstico por imagen , Ventrículos Cardíacos/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Contracción Miocárdica , Infarto del Miocardio/diagnóstico por imagen , Cintigrafía , Pertecnetato de Sodio Tc 99mRESUMEN
Differential assessment of T wave changes in response to exercise testing and contrast ventriculography appraising the condition of the coronary bed and intracardiac hemodynamics was performed in 117 patients with coronary heart disease. It is suggested that the T amplitude increasing twofold and more or reversion of the T wave in response to exercise should be considered as an evidence of abnormality.