RESUMEN

Because plants do not possess a defined germline, deleterious somatic mutations can be passed to gametes, and a large number of cell divisions separating zygote from gamete formation may lead to many mutations in long-lived plants. We sequenced the genome of two terminal branches of a 234-year-old oak tree and found several fixed somatic single-nucleotide variants whose sequential appearance in the tree could be traced along nested sectors of younger branches. Our data suggest that stem cells of shoot meristems in trees are robustly protected from the accumulation of mutations.

Asunto(s)

Genes de Plantas , Mutación , Quercus/genética , Árboles/genética , Longevidad/genética , Meristema/citología , Meristema/genética , Tasa de Mutación , Brotes de la Planta/citología , Brotes de la Planta/genética , Polimorfismo de Nucleótido Simple , Quercus/citología , Árboles/citología