RESUMEN
In May 2012, the first authenticated cases of active chikungunya virus infection were detected in Champasak Province, Southern Laos. Analysis of series of human samples and mosquito specimens collected during the outbreak and over the year that followed the emergence enabled the drawing up of a map of the progression of CHIKV and the establishment of a full genetic characterization of the virus.
Asunto(s)
Aedes/virología , Fiebre Chikungunya/epidemiología , Animales , Biomarcadores/sangre , Fiebre Chikungunya/sangre , Fiebre Chikungunya/patología , Virus Chikungunya/genética , Virus Chikungunya/aislamiento & purificación , Brotes de Enfermedades , Humanos , Laos/epidemiología , Mosquitos Vectores , Filogenia , Estudios SeroepidemiológicosRESUMEN
During the 2012 epidemic of dengue in Vientiane capital, Lao PDR, a major serotype switch from dengue 1 to 3 was observed. A molecular epidemiology study demonstrated that dengue 3 remained the predominant serotype in 2013, but also revealed the co-circulation of two genotypes, supporting the hypothesis of multiple geographic origins of dengue 3 strains circulating in Vientiane capital.