1.
Org Biomol Chem
; 16(10): 1672-1678, 2018 03 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29446433
RESUMEN
An efficient asymmetric synthesis of trans-4,5-disubstituted γ-butyrolactones from aldehydes and enantioenriched γ-carbamate alkenylboronates is reported. The cornerstone of this strategy is the implementation of sequential [3,3]-allyl cyanate rearrangement/allylboration/nucleophilic addition/cyclisation reactions. Diverse γ-butyrolactones such as the flavouring compounds, (+)-trans-whiskey lactone and (+)-trans-cognac lactone, as well as an advanced intermediate towards the first synthesis of natural products, (-)-nicotlactone B and (-)-galbacin, have thus been obtained.
2.
Methods Find Exp Clin Pharmacol
; 19 Suppl A: 37-41, 1997.
Artículo
en Inglés
| MEDLINE
| ID: mdl-9403855