RESUMEN

The effect of alcohol on the pharmacokinetics of phenoxymethylpenicillin was studied in six healthy volunteers. Ethanol had no influence on peak penicillin serum concentrations, times of the penicillin peaks, elimination half-lives (t1/2), AUC0-8h values and 24-h urinary excretion.

Asunto(s)

Etanol/farmacología , Penicilina V/farmacocinética , Administración Oral , Adulto , Cromatografía Líquida de Alta Presión , Interacciones Farmacológicas , Etanol/administración & dosificación , Femenino , Semivida , Humanos , Masculino , Penicilina V/sangre , Penicilina V/orina