RESUMEN

A reassortant influenza A(H1N1) virus of swine origin distinct from the pandemic H1N1 2009 strain was isolated from 3 patients, all of whom worked at the same large hog operation in Saskatchewan, Canada. The genomic composition of the isolates has not been previously reported, to our knowledge, and was the product of a genetic reassortment between seasonal H1N1 and triple-reassortant influenza virus that emerged in North American swine during the late 1990s. The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007.

Asunto(s)

Glicoproteínas Hemaglutininas del Virus de la Influenza/genética , Subtipo H1N1 del Virus de la Influenza A/genética , Gripe Humana/virología , Neuraminidasa/genética , Virus Reordenados/genética , Adulto , Animales , Secuencia de Bases , Femenino , Humanos , Masculino , Datos de Secuencia Molecular , Infecciones por Orthomyxoviridae/veterinaria , Infecciones por Orthomyxoviridae/virología , Filogenia , Virus Reordenados/patogenicidad , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Saskatchewan/epidemiología , Porcinos/virología