RESUMEN
El tratamiento trombolítico se ha consolidado en los últimos años como una opción terapéutica efectiva en el ictus isquémico. Existen variadas experiencias en la administración de tratamiento trombolítico en hospitales básicos y rurales. Describimos cuatro casos en los que hemos realizado tratamiento trombolítico en un hospital básico. Hemos utilizado un protocolo estricto de administración basado en el protocolo descrito en el National Institute of Neurological Disorders and Stroke (NINDS) rt-PA stroke study. No hemos detectado ni complicaciones hemorrágicas ni violaciones del protocolo. Concluimos que este protocolo nos ha permitido ofrecer un tratamiento seguro a nuestros pacientes con ictus isquémico (AU)
Thrombolytic drugs have been used in recent years as an effective therapeutic option in ischemic stroke. There are several experiences with the administration of thrombolytic therapy in basic and rural hospitals. We are describing our experience with four cases in which this treatment was used in our basic hospital during the last three years. We used a strict protocol described in the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA stroke study. No intracranial hemorrhage or protocol violations were detected. We conclude that this protocol has allowed us to offer safe treatment to our ischemic stroke patients (AU)
Asunto(s)
Humanos , Terapia Trombolítica/métodos , Isquemia Encefálica/terapia , Accidente Cerebrovascular/terapia , Pautas de la Práctica en Medicina , Protocolos Clínicos/normas , Atención Primaria de Salud/métodosRESUMEN
Thrombolytic drugs have been used in recent years as an effective therapeutic option in ischemic stroke. There are several experiences with the administration of thrombolytic therapy in basic and rural hospitals. We are describing our experience with four cases in which this treatment was used in our basic hospital during the last three years. We used a strict protocol described in the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA stroke study. No intracranial hemorrhage or protocol violations were detected. We conclude that this protocol has allowed us to offer safe treatment to our ischemic stroke patients.
Asunto(s)
Isquemia Encefálica/tratamiento farmacológico , Servicio de Urgencia en Hospital , Fibrinolíticos/uso terapéutico , Terapia Trombolítica , Enfermedad Aguda , Anciano , Isquemia Encefálica/complicaciones , Hemorragia Cerebral/inducido químicamente , Hemorragia Cerebral/prevención & control , Protocolos Clínicos , Femenino , Fibrinolíticos/administración & dosificación , Fibrinolíticos/efectos adversos , Adhesión a Directriz , Hospitales Comunitarios , Humanos , Masculino , Persona de Mediana Edad , Paresia/etiología , España , Terapia Trombolítica/efectos adversos , Resultado del TratamientoRESUMEN
Two experiments are described investigating learning and orientation in the triatomine Rhodnius prolixus. In experiment 1, Pavlovian conditioning was investigated. The experiment differed from our previous work in that the intensity of the conditioned and unconditioned stimuli were reduced and the number of training trials increased. Once again, no evidence for Pavlovian conditioning was found. In experiment 2, an "orientation arena" was developed in which the orientation of R. prolixus to a human forearm was investigated when an area of the forearm was impregnated with the odor of ruda or almizcle compared to a forearm with no odor. The various paths of the animal from the bottom of the arena until ascending and piercing the forearm, located at the top of the arena, was scored using a grid system and videotaped. The results indicated that under the no odor condition R. prolixus predominately travels in a straight line from the bottom of the arena to the top where the forearm is located. In contrast, the most variable number of paths occurred with exposure to ruda. Exposure to almizcle elicited straight line paths but other paths were evident, although not as variable as that observed with ruda.