RESUMEN
Los síndromes paraneoplásicos neurológicos son un grupo de trastornos poco frecuentes y heterogéneos que afectan al sistema nervioso y que ocurren en pacientes con una neoplasia maligna, generalmente oculta. Presentamos el caso de una mujer diagnosticada de encefalitis límbica paraneoplásica con presencia de anticuerpos anti-Hu que permitió diagnosticar un cáncer de pulmón oculto (AU)
Paraneoplastic neurologic syndromes are a group of disorders, rare and heterogeneous, affecting the nervous system and usually occur in occult cancer patients. We report the case of a woman diagnosed with paraneoplastic limbic encephalitis and presence of anti-Hu antibodies that allowed to detect occult lung cancer (AU)
Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Neoplasias Pulmonares/complicaciones , Neoplasias Pulmonares/diagnóstico , Proteínas ELAV/administración & dosificación , Proteínas ELAV/análisis , Proteínas ELAV/metabolismo , Proteínas del Tejido Nervioso/análisis , Proteínas del Tejido Nervioso/metabolismo , Diagnóstico Diferencial , Autoanticuerpos/análisis , Autoanticuerpos/sangre , Técnica del Anticuerpo Fluorescente Indirecta/métodos , Western Blotting/métodosRESUMEN
BACKGROUND: Single incision laparoscopic surgery has increased recently due to successful results, achieved in several procedures. The aim of the present work is to present the first case in which single incision laparoscopy is used for the drainage of an amoebic liver abscess. CLINICAL CASE: A 44-year-old man presented with intense right upper quadrant pain, generalised jaundice, tachycardia, fever, hepatomegaly and a positive Murphy's sign. Laboratory results revealed an increased plasma bilirubin, elevated alkaline phosphatase and transaminases, leucocytosis, negative viral panel for hepatitis, and positive antibodies against Entamoeba histolytica. On an abdominal computed tomography a 15 × 12.1 cm hypodense lesion was observed in the patient's liver, identified as an amoebic liver abscess. Analgesics and antibiotics were started and subsequently the patient was submitted to laparoscopic drainage of the abscess using a single port approach. Drainage and irrigation of the abscess was performed. Four days later the patient was discharged without complications. CONCLUSION: Management of amoebic liver abscess is focused on the elimination of the infectious agent and obliteration of the abscess cavity in order to prevent its complications, especially rupture. Laparoscopic surgery has proved to be a safe and effective way to manage this entity.