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1.
Ann Transl Med ; 7(23): 778, 2019 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-32042794

RESUMEN

BACKGROUND: Cardiac surgery remains the gold standard treatment for select cohorts of patients with coronary artery and valvular heart diseases. It induces an acute systemic inflammatory response due to cardiopulmonary bypass (CPB), myocardial arrest, and surgical trauma. There is growing evidence that increased inflammation leads to greater complications and poorer outcomes for patients post cardiac surgery. Neutrophil/lymphocyte ratio (NLR) is a promising marker of inflammation. This study assessed if NLR could predict postoperative atrial fibrillation and acute kidney injury after cardiac surgery. METHODS: A retrospective review of patients undergoing first-time on-pump cardiac surgery was performed. Postoperative atrial fibrillation and acute kidney injury within 7 days of surgery was recorded. Preoperative, day 1, and day 2 NLR were recorded. Potential confounders such as age, sex, comorbidities, and operative factors were included in univariate analysis. Backwards stepwise multivariate regression analysis was performed to identify independent predictors of these complications. RESULTS: Nine hundred and six patients were included for analysis. Higher preoperative NLR was significantly associated with postoperative atrial fibrillation. Day 1 and day 2 NLR were associated with postoperative atrial fibrillation in analyses including all patients. Older age, male gender, preexisting atrial arrhythmias, and higher EuroSCORE II also had a significant association. Diabetes mellitus was protective for postoperative arrhythmias. Preoperative NLR was not significantly associated with acute kidney injury. Day 2 NLR, older age, higher EuroSCORE II, and longer CPB time were independently associated with acute kidney injury post cardiac surgery. CONCLUSIONS: Higher preoperative and postoperative NLRs are associated with higher rates of complications post cardiac surgery.

2.
J Plast Reconstr Aesthet Surg ; 63(1): e51-3, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-19527946

RESUMEN

Plastic surgeons specialize in working closely with other surgical colleagues to help solve clinical problems. In this case, we performed surgical stabilisation of a large flail chest fragment in conjunction with the cardiothoracic surgical team, using the mini-plating set more commonly used for hand fracture fixation. The use of this fixation system for flail chest has not previously been described, but offers advantages over other reported methods, primarily by dispensing with the need for an extensive thoracotomy incision and by providing robust stabilisation without the presence of prominent hardware.


Asunto(s)
Placas Óseas , Tórax Paradójico/cirugía , Accidentes de Trabajo , Adulto , Tórax Paradójico/diagnóstico por imagen , Tórax Paradójico/etiología , Humanos , Masculino , Tomografía Computarizada por Rayos X
3.
Heart Surg Forum ; 9(6): E893-6, 2006.
Artículo en Inglés | MEDLINE | ID: mdl-17599889

RESUMEN

BACKGROUND: The placement of preoperative intra-aortic balloon pumps (IABP) in high-risk patients has been described, although controversy remains regarding the appropriate selection of these patients. The EuroSCORE is a proven predictor of operative mortality for coronary artery bypass surgery (CABG). Our objective was to assess whether patients with a preoperative IABP had a 30-day mortality consistent with their predicted mortality. METHODS: Sixty-sis patients who had had an IABP sited while undergoing CABG were retrospectively identified. The additive EuroSCORE was calculated with omission of the IABP preoperative placement score of 3 points. Patients with a EuroSCORE <5 were considered low risk, and those > or = m5 as high risk. RESULTS: High-risk patients with preoperative IABP placement had a significantly lower mortality (1/16, 6.25%) than predicted. The predicted versus actual mortality was 12.6% versus 6.25%. CONCLUSION: Correct identification of appropriate patients who would benefit from pre-emptive placement of IABP could potentially be performed using the EuroSCORE.


Asunto(s)
Puente de Arteria Coronaria/mortalidad , Indicadores de Salud , Contrapulsador Intraaórtico , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Selección de Paciente , Valor Predictivo de las Pruebas , Cuidados Preoperatorios , Estudios Retrospectivos , Medición de Riesgo
4.
Interact Cardiovasc Thorac Surg ; 2(4): 569-71, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-17670125

RESUMEN

A case of transection of the origin of the innominate artery with an associated head injury following blunt thoracic injury is presented. The patient had been the unrestrained driver in a road traffic accident. Investigation demonstrated embolic damage to the brain parenchyma. Early surgical repair employing cardiopulmonary bypass and hypothermic circulatory arrest was successfully performed without extension of the neurological injury.

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