RESUMEN
The article provides the current epidemiological characteristics of viral hepatitis B and C and the existing problems of registering parenteral viral hepatitides in Russia. It justifies the need for introducing a uniform federal registry of patients with viral hepatitis B and C and shows prospects for its introduction.
Asunto(s)
Hepatitis B/epidemiología , Hepatitis C/epidemiología , Sistema de Registros/estadística & datos numéricos , Humanos , Morbilidad , Federación de Rusia/epidemiologíaRESUMEN
High-pressure helium reduces the latex-induced activated chemiluminescence of diluted human blood. This effect is more noticeable, when lucigenin rather than luminol is used as the activator of chemiluminescence. The effect lessens in the presence of Mg2+ but not Ca2+. The data suggest the association of this effect with actin polymerization in leucocytes phagocytosing the latex particles.
Asunto(s)
Helio/química , Látex/farmacología , Leucocitos/efectos de los fármacos , Leucocitos/metabolismo , Humanos , Iones/química , Mediciones Luminiscentes , PresiónRESUMEN
One hundred and forty-four new cases of pulmonary tuberculosis were examined. The examination revealed the following neurological syndromes: vegetovascular dystonia, disseminated cerebral microsymptoms, focal lesion of the brain, sensory polyneuropathy. The presence of positive specific basophilic degranulation reactions and intracutaneous tuberculin test suggests that the body shows allergic reactions in response to Mycobacteria tuberculosis. And since connective tissue that presents in the vessels and tunics in the nervous system is involved into a pathological process in allergy, neurological disorders are always secondary in tuberculosis and due to the primary vascular wall lesion that following the type of secondary allergic vasculitis.
Asunto(s)
Enfermedades del Sistema Nervioso/etiología , Tuberculosis del Sistema Nervioso Central/etiología , Tuberculosis Pulmonar/complicaciones , Adulto , Encefalopatías/etiología , Trastornos Distónicos/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mycobacterium tuberculosis/inmunología , Enfermedades del Sistema Nervioso/inmunología , Polineuropatías/etiología , Polineuropatías/inmunología , Síndrome , Prueba de Tuberculina , Tuberculosis del Sistema Nervioso Central/inmunología , Tuberculosis Pulmonar/inmunologíaRESUMEN
Plasma lipid oxidation (LPO) and antioxidative system were examined in test divers who made imitation diving in the pressure chamber to the depth of 250 meters. Imitation diving showed higher iron levels, followed by a rise in the concentration of primary LPO products. There were no increases in the levels of secondary LPO products probably due to the fact that the ceruloplasmin-transferrin system released active iron from the reaction and that peroxy radicals were inactivated by SH groups.
Asunto(s)
Antioxidantes/metabolismo , Buceo/fisiología , Peroxidación de Lípido , Estudios de Seguimiento , Humanos , Hierro/sangre , Peroxidación de Lípido/fisiología , Proyectos de InvestigaciónAsunto(s)
Argón/farmacología , Metabolismo Energético , Hipoxia/metabolismo , Corteza Motora/metabolismo , Nitrógeno/farmacología , Administración por Inhalación , Animales , Argón/administración & dosificación , Hipoxia/enzimología , Corteza Motora/enzimología , NADH Deshidrogenasa/metabolismo , Nitrógeno/administración & dosificación , Oxidación-Reducción , Fosforilación , Ratas , Succinato Deshidrogenasa/metabolismoRESUMEN
The effect of high pressure on the Fe-ascorbate-induced lipid peroxidation in liposome suspensions has been studied. It was found that hydrostatic or helium pressure up to 140 bar increases the rate of MDA accumulation in this model system. This effect is assumed to be connected with the gain in polarity of the lipid bilayer under hyperbaric conditions.
Asunto(s)
Membrana Dobles de Lípidos , Peroxidación de Lípido , Liposomas , Animales , Ácido Ascórbico/farmacología , Embrión de Pollo , Presión Hidrostática , Peroxidación de Lípido/efectos de los fármacos , Malondialdehído/metabolismoRESUMEN
Ischemia and reoxygenation were experimentally induced in thin liver sections. It has been shown that free iron decompartmentalization takes place 30 min after the induction of ischemia, with no lipid peroxidation activation observed. In reoxygenation, activation of lipid peroxidation and decrease in free iron concentration take place in the liver cells. It is suggested that free iron accumulation in the tissues during ischemia causes lipid peroxidation activation during reoxygenation.