Asunto(s)
Anestesiología , Cuidados Críticos , Medicina , Especialización , Anestesiología/tendencias , Humanos , Federación de RusiaRESUMEN
The use of the method of autologous blood photomodification in surgery is discussed on basis of generalized experience of the Leningrad Research-Practical Center of Blood Photomodification (3,000 procedures conducted in over 2,000 patients). The current state of the problem, the main mechanisms of the therapeutic action of the procedure, and the clinical efficacy of the method in various surgical diseases are dealt with. The possible complications and the means of their prevention are deal with. The methodological aspects of research are discussed. The authors define the main problems which must be solved in order to raise the efficacy of using photomodification of autologous blood in surgery.
Asunto(s)
Transfusión de Sangre Autóloga , Sangre/efectos de la radiación , Procedimientos Quirúrgicos Operativos , Infección de la Herida Quirúrgica/radioterapia , Toxemia/radioterapia , Terapia Ultravioleta/métodos , Humanos , Procedimientos Quirúrgicos Operativos/efectos adversos , Infección de la Herida Quirúrgica/prevención & control , Toxemia/prevención & controlRESUMEN
A team of anesthesiologists and intensive care specialists of the Leningrad district hospital has in the course of 5 years (1984-1988) rendered medical aid to 2163 critically ill children. 1374 of them were transported to the district hospital and other medical centres. 82.3% of children were under 3 years of age. The majority of children had severe respiratory disturbances (52.5%). Guidelines for safe interhospital transportation of critically ill children have been elaborated, which made it possible to avoid deterioration of the patients' condition at interhospital stage. The term "non-transportable" is recommended to be replaced by "transportation inadvisable".
Asunto(s)
Cuidados Críticos , Transferencia de Pacientes/métodos , Pediatría , Preescolar , Humanos , Recién Nacido , Federación de RusiaRESUMEN
Clinical observations in 99 patients and 74 experiments in cats enabled the authors to suggest that nondepolarizing myorelaxants when used in combination affected different portions of cholinergic receptors of the end plate of motor nerves causing greater inhibition of neuromuscular transmission. So an associated simultaneous application of such myorelaxants as tubocurarine and tercuronium as well as tercuronium and Arduan in special sub-blocking doses gives a complete relaxation of skeletal muscles without side effects which allows such methods to be recommended in surgical practice for anesthetic maintenance of operations on high risk patients.
Asunto(s)
Relajantes Musculares Centrales/efectos adversos , Adolescente , Adulto , Anciano , Animales , Gatos , Relación Dosis-Respuesta a Droga , Evaluación de Medicamentos , Evaluación Preclínica de Medicamentos , Quimioterapia Combinada , Electromiografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Contracción Muscular/efectos de los fármacos , Unión Neuromuscular/efectos de los fármacos , Transmisión Sináptica/efectos de los fármacosRESUMEN
Inhalation of diethyl ether and intraperitoneal injection of hexenal in doses that provide a surgical state of anesthesia are accompanied by changes in the regional tone of the resistive blood vessels as well as by those in the ratio between the nutritive and shunting fractions of the blood flow in organs and tissues. The increase in the rate and enlargement of the area of transcapillary metabolism in the brain and myocardium (notwithstanding the decrease of the total blood flow in these organs) by means of the increased shunting fractions of the blood flow in vast skin and skeletal muscle areas are considered to be the most important events. Diethyl ether and hexenal cause different changes in the hepatic and renal hemodynamics.