RESUMEN

Current diagnostic capabilities and limitations of fluorescence endomicroscopy in the cervix are assessed by qualitative and quantitative image analysis. Four cervical tissue types are investigated: normal columnar epithelium, normal and precancerous squamous epithelium, and stromal tissue. This study focuses on the perceived variability within and the subtle differences between the four tissue groups in the context of endomicroscopic in vivo pathology. Conclusions are drawn on the general ability to distinguish and diagnose tissue types, on the need for imaging depth control to enhance differentiation, and on the possible risks for diagnostic misinterpretations.

Asunto(s)

Cuello del Útero/citología , Cuello del Útero/diagnóstico por imagen , Microscopía Confocal/métodos , Microscopía Fluorescente/métodos , Células Epiteliales/citología , Diseño de Equipo , Femenino , Humanos , Proyectos Piloto , Lesiones Intraepiteliales Escamosas de Cuello Uterino/diagnóstico por imagen