RESUMEN

This article reports the case of a 55-year-old man who presented with aphasia caused by intracerebral lesions and had a history of pulmonary sarcoidosis. Due to nonsteroidal anti-inflammatory drug-resistant spondyloarthritis TNF-alpha inhibitor treatment was started after a negative tuberculosis screening. Subsequently the patient developed pulmonary tuberculosis and cerebral tuberculoma reactivated by the TNF-alpha inhibitor therapy accompanied by pulmonary sarcoidosis with sacroiliitis and oligoarthritis. This case report emphasises the risk of atypical tuberculosis infections under TNF-alpha inhibitors despite negative results of tuberculosis screening.

Asunto(s)

Antiinflamatorios/efectos adversos , Sacroileítis/complicaciones , Sarcoidosis/complicaciones , Tuberculoma Intracraneal/inducido químicamente , Tuberculoma Intracraneal/diagnóstico , Factor de Necrosis Tumoral alfa/antagonistas & inhibidores , Antiinflamatorios/uso terapéutico , Humanos , Masculino , Persona de Mediana Edad , Sacroileítis/tratamiento farmacológico , Sarcoidosis/tratamiento farmacológico , Resultado del Tratamiento