RESUMEN
Hypolipidemic and antihyperlipidemic effect from an aqueous extract Pachyptera hymenaea were studied and volatile constituents from the extract were analysed by GC-MS. Extract was administered to normal and diet-induced hypercholestrolemic rats for 28days and serum lipid profiles were estimated. An oral dose, at 200mg/kg/day, resulted in significant declines in plasma LDL-cholesterol, triglycerides (TG) and total cholesterol (TC) by 44.0%, 27.9% and 28.1% respectively, compared to normal rats. An extract at 400mg/kg/day, to hypercholestremic rats, resulted in significant declines in plasma TC, LDL-cholesterol and TG, by 66.1%, 60.0% and 57.6% respectively, compared to a hypercholestremic control. GC-MS study of the volatile oil revealed the presence of two main organosulphur compounds, diallyldisulphide (65.9%, v/v) and diallyltrisulphide (29.6%, v/v). Evidently the extract possesses pronounced hypolipidemic and antihyperlipidemic effects which are comparable to those of atorvastatin. These effects are due to the presence of organosulphur compounds, flavonoids and polyphenols present in the extract.
RESUMEN
A cross sectional observation study was carried out in primary school children of slum dwelling area of Kathmandu Valley which included 454 students. The aim of study was to find out morbidity in habit disorders in age group of 6-10 years so that early detection will be helpful to correct them to prevent it from further personality maladjustment. There was no statistical difference in gender wise habit disorders. The morbidity is due to multiple factors of physico- social environment. However severity of disease is not more here in this area.
Asunto(s)
Trastornos de la Conducta Infantil/epidemiología , Áreas de Pobreza , Niño , Estudios Transversales , Femenino , Humanos , Masculino , Nepal/epidemiologíaRESUMEN
The authors reviewed the all referral cases from different inpatient and outpatient department, in Nepal Medical College and Teaching Hospital. It was a descriptive study. There were 484 referred cases during the study period. Around half the referral were from department of medicine (49.8%), surgery (11.2%), Eye/ENT (10.3%). The referral rate was 1.4%, with an average three cases per day. Among the referral cases depression was diagnosed in 26.9%, anxiety in 15.5% and substance related problem in 14.5%. The consultation liaison psychiatry service is satisfactorily used. Depression, substance use problem, anxiety, deliberate self harm is the main diagnoses in liaison psychiatry.