1.
Vopr Virusol
; 31(4): 400-4, 1986.
Artículo
en Ruso
| MEDLINE
| ID: mdl-3020805
Asunto(s)
Infecciones por Paramyxoviridae/tratamiento farmacológico , Inhibidores de Proteasas/uso terapéutico , Animales , Antígenos Virales/análisis , Niño , Evaluación de Medicamentos , Evaluación Preclínica de Medicamentos , Cobayas , Humanos , Virus de la Parainfluenza 3 Humana/efectos de los fármacos , Virus de la Parainfluenza 3 Humana/inmunología , Virus de la Parainfluenza 3 Humana/fisiología , Inhibidores de Proteasas/farmacología , Proteínas Virales/antagonistas & inhibidores , Replicación Viral/efectos de los fármacos
2.
Vopr Virusol
; 31(1): 45-51, 1986.
Artículo
en Ruso
| MEDLINE
| ID: mdl-3008440
RESUMEN
The structure of human parainfluenza type 3 virus was studied by electron microscopy and virion fractionation by treatment with a detergent and high ionic strength. The protein spectrum of the virus was studied. The presence of 6 structural proteins was revealed of which two, HN and F, are glycoproteins. Intracellular cleavage of F0 protein into F1+2 proteins was demonstrated in a pulse-chase experiment. A tighter binding of HN protein than of F protein with the virus lipoprotein membrane was observed which may be useful for obtaining purified F protein preparations.