RESUMEN
Study on health status of 156 Vietnamese military pilots on Russian modern jet planes (Su-22, Su-27, Su-30, MiG-21B). The results showed that unprofitable factors in working environment (acceleration, radiation, high temperature, humidity, noise) have an impact on the health of pilots during the flight, leading to deterioration of professional health and physiological functions (cardiovascular, respiratory and nervous system) and obesity of pilots after 35 years old. Basing on the studies, we suggested some measures for health protecting, safety of flight and prolonging flight-activity of pilots (training in decompression chamber, vestibular training) and balance in food ration for prevention of professional diseases.
Asunto(s)
Aceleración/efectos adversos , Adaptación Fisiológica , Calor/efectos adversos , Hipergravedad/efectos adversos , Personal Militar , Ruido/efectos adversos , Adulto , Aeronaves , Humanos , Masculino , Obesidad/fisiopatología , Federación de Rusia , VietnamRESUMEN
Goal and objectives of the study was comparative description and establishment of dose-time dependence of changes in permeability of the hemato-encephalic barrier (HEB) in phylogenetically different parts of the brain cortex, i.e. new (Fr2 and Cg3), old (hippocampal fields CA1-CA4 and dentate fascia) and paleocortex (piriform cortex) following exposure to 0.1; 0.2; 0.5 and 1 Gy of ionizing radiation (dose rate = 50 cGy). Dependence of microvessels permeability on dose, post-exposure time and cortex phylogenetic age was established. Changes in brain microvessels, in the phylogenetically young cortex in particular, produced by 0.5 Gy and 1 Gy remained uncompensated till the end of investigation. Pronounced changes persisted over the period of one year after radiation exposure; complete recovery was not observed even in the phylogenetically old cortex.
Asunto(s)
Barrera Hematoencefálica/efectos de la radiación , Encéfalo/efectos de la radiación , Microvasos/efectos de la radiación , Radiación Ionizante , Animales , Encéfalo/irrigación sanguínea , Hipocampo/efectos de la radiación , Masculino , Permeabilidad , Dosis de Radiación , Ratas , Factores de TiempoRESUMEN
The investigation has the aim to compare reactions of phylogenetically different parts of the brain cortex to single and fractionated irradiation by 1 Gy. The focus is primarily laid on unveiling the morphological stage of radiation-induced changes in the cortex. A hundred of 100 nubilous male rats with the body mass of 200-230 g were subject to whole-body uniform single and fractionated gamma-irradiation (total dose absorption over 5 days) with MeV spectrum 1.2 at 1 Gy (dose rate--50 cGy/h). Sampling of cortex motoria secundaria, cortex prelimbicus, hippocampus fields CA1-CA4, dentate fascia and cortex piriformis was conducted in a day, 6, 12 and 18 months after exposure. Brain sections were fixated in 10% formalin solution and then embedded in paraffin. Paraffin sections were stained by Karachi hematoxylin-eosin for review and Nissl methylene blue for cytoarchitectonics studies. In samples of every animal, 300 neurocytes were counted with careful examination of distinct changes in cell form, uniformity of cytoplasm staining, level of nucleus and nucleolus differentiation and Nissl substance basophilia. Late reparation of damaged neurocytes was observed after fractionated irradiation. Evidence of changes and time of compensation of damaged neurocytes correlate with method of irradiation, length of post-irradiation period and phylogenetic age of the cortex.