RESUMEN

An investigation of the action of phenylephrine on the transport of sodium across the human cell membrane is reported. The characteristic parameters of drug-receptor interaction -- the maximal response and ED50 -- were calculated based on the conventional dose-response plot and its linear transformations. The results obtained were in good agreement with other experimental findings.

Asunto(s)

Eritrocitos/efectos de los fármacos , Fenilefrina/farmacología , Receptores Adrenérgicos alfa/efectos de los fármacos , Receptores Adrenérgicos/efectos de los fármacos , Transporte Biológico Activo/efectos de los fármacos , Eritrocitos/metabolismo , Humanos , Técnicas In Vitro , Receptores Adrenérgicos alfa/sangre , Sodio/sangre