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J Clin Neurosci ; 81: 227-233, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-33222921

RESUMEN

Caudaequinatumors are histologically diverse. International Classification of Diseases for Oncology (ICD-O3) confers dedicated site code (C72. 1) for cauda equina. This code is excluded during analyses of other primary spinal cord tumors. In this retrospective study, the Surveillance, Epidemiology and End Results (SEER) data for primary cauda equina tumors (PCET, C72. 1) excluding the tumors of spinal meninges (C70. 1) from 1992 to 2015 were reviewed. Demographic characteristics, tumor types, and clinical outcomes were analyzed using univariable analysis. Overall survival was estimated using Kaplan-Meier methods and compared for age, histology and treatment type. 293 patients with PCET met inclusion criteria. The most common tumors comprised schwannoma (32%), myxopapillary ependymoma (21%), malignant ependymoma (22%). The median age at diagnosis was 50 years (range < 1 year to 98 years), 57% of patients were males. 77% of the patients underwent surgery. Median follow up time for these patients was 70 months. Of the 293 patients, 250 (85%) were living at the end of 2015. The cause of death was tumor or CNS related in 15 patients. 136 patients were followed for <5 years, of which 102 were censored and 34 died (11.6%) before 5 years. Using univariable analysis, age at diagnosis (Hazard Ratio, HR 1.05; confidence interval, CI 1.03-1.07; p < 0.001), malignant tumor type (HR 2.88, CI 1.15-7.19, p = 0.0239) and absence of surgical intervention (HR 2.54, CI1.26-5.11, p = 0.0092) were predictors of increased mortality. Although most patients did well, older age and lack of surgical intervention were associated with worse survival.


Asunto(s)
Cauda Equina/patología , Programa de VERF , Neoplasias de la Médula Espinal/diagnóstico , Neoplasias de la Médula Espinal/mortalidad , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Ependimoma/diagnóstico , Ependimoma/mortalidad , Ependimoma/cirugía , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Neurilemoma/diagnóstico , Neurilemoma/mortalidad , Neurilemoma/cirugía , Valor Predictivo de las Pruebas , Estudios Retrospectivos , Programa de VERF/tendencias , Neoplasias de la Médula Espinal/cirugía , Tasa de Supervivencia/tendencias , Resultado del Tratamiento , Adulto Joven
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