1.
J Pain Symptom Manage
; 45(5): e7-8, 2013 May.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23535323
Asunto(s)
Neoplasias Encefálicas/complicaciones , Neoplasias Encefálicas/tratamiento farmacológico , Epilepsia/tratamiento farmacológico , Epilepsia/etiología , Piracetam/análogos & derivados , Anciano , Anticonvulsivantes/administración & dosificación , Relación Dosis-Respuesta a Droga , Femenino , Humanos , Inyecciones Subcutáneas , Levetiracetam , Cuidados Paliativos , Piracetam/administración & dosificación , Resultado del Tratamiento
2.
Support Care Cancer
; 21(2): 649-52, 2013 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23207922
RESUMEN
Within an oncology setting, certain chemotherapy drugs, such as cisplatin, may lead to magnesium loss causing nephropathy. Neurological and cardiovascular symptoms caused by hypomagnesaemia are well known. The relationship between serious hypomagnesemia and severe pain is not well documented but nevertheless, when faced with unexplained episodes of pain which do not respond to powerful analgesics, it is important to review blood magnesium levels. We present two cases of opioid-refractory pain attacks. Patients received drugs which have been linked to hypomagnesemia. In both cases, endovenous magnesium replacement led to a drastic improvement in pain management.