RESUMEN
In order to evaluate the relationship between cellular and humoral immunity, washings from the gingival sulcus were analyzed in 15 patients with catarrhal gingivitis and 15 subjects with intact periodontium aged 19-22 years. The results indicate a close relationship between local immunity and humoral and cellular defense factors. It seems that decreased IgA level, complement component, and increased activities of C-reactive protein and antistreptolysin-O are the key factors in the development of chronic gingivitis. Permanent bacterial aggression leads to dysfunction of phagocytic and epithelial cells.
Asunto(s)
Líquido del Surco Gingival/inmunología , Gingivitis/inmunología , Adulto , Antiestreptolisina/análisis , Proteína C-Reactiva/análisis , Humanos , Inmunidad Celular , Inmunoglobulina A/análisisRESUMEN
Differential diagnosis between essential hypertension and secondary arterial hypertension (AH) that developed in the presence of chronic pyelonephritis was made in 12 patients with AH and the urinary syndrome (leukocyturia and bacteriuria). With that purpose in view for revealing functional renal asymmetry, a study was made of the effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) in each kidney separately based on computation of 99Tc-DTPA and 131I-hippuran clearances. Some patients in whom AH was later regarded as essential manifested practically equal values of the ERPF and GFR from both sides, with the real characteristics of the latter ones being little different from the respective populational values calculated by computer bearing in mind the body surface of those patients. The other patients' group showed, along with a decrease of the total ERPF and GFR, a dramatic asymmetry of the intrarenal hemodynamics of both ERPF and GFR, which is fairly characteristic of chronic pyelonephritis. This allows the syndrome of AH to be regarded in those patients as secondary.
Asunto(s)
Hipertensión Renal/diagnóstico , Riñón/fisiopatología , Anciano , Enfermedad Crónica , Diagnóstico Diferencial , Femenino , Tasa de Filtración Glomerular , Hemodinámica/fisiología , Humanos , Hipertensión Renal/etiología , Hipertensión Renal/fisiopatología , Masculino , Persona de Mediana Edad , Pielonefritis/complicaciones , Pielonefritis/diagnóstico , Pielonefritis/fisiopatología , Circulación RenalRESUMEN
Physical characteristics of bone marrow cells of normal donors were comparatively studied with those of children with immune neutropenia. As a result of the bone marrow cell separation in the density gradient according to their sedimentation rate, fractions enriched with cells of one histogenetic series (lymphoid, erythroid and granulocytic) were obtained. Electrophoretic mobility of immature granulocytes in normal donors differed from that in children with immune neutropenia.
Asunto(s)
Agranulocitosis/patología , Células de la Médula Ósea , Neutropenia/patología , Sedimentación Sanguínea , Movimiento Celular , Separación Celular , Preescolar , Enfermedad Crónica , Eritrocitos/citología , Granulocitos/citología , Humanos , Lactante , Linfocitos/citología , Neutropenia/inmunologíaRESUMEN
The effect of heparin on the thymidine-3H incorporation into the cells of the continous line A-1 was studied. Cell incubation in medium 199 containing heparin (1--200 units per ml) did not lead to reduction of the labeled nuclei percentage; the duration of the G2 and S periods also failed to change in comparison with control. However, the incorporation intensity of thymidine-3H (the mean number of granules per one labeled nucleus) was decreased significantly. The data obtained indicated that heparin influenced the plasmalemma permeability, but had no effect on the DNA synthesis. The antimitotic action of heparin was apparently due to its influence on the cell surface.