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Parasitol Res ; 102(6): 1277-9, 2008 May.
Artículo en Inglés | MEDLINE | ID: mdl-18273644

RESUMEN

In this research, (-)-usnic acid and (+)-usnic acid, commonly encountered lichen secondary metabolites, were evaluated for their insecticidal effects against the larvae of Culex pipiens L. (Diptera: Culicidae) under laboratory conditions. Both compounds showed strong larvicidal activity and caused 100% mortality on third-fourth larval stages of the species at 24 h at the doses of 5 and 10 ppm. Bioassays with (-)- and (+)-usnic acids against larvae of C. pipiens revealed that the LC50 values were 0.8 and 0.9 ppm, respectively. The results suggest that lichen compounds could be useful in the search of new insecticides.


Asunto(s)
Benzofuranos/farmacología , Culex/efectos de los fármacos , Insecticidas/farmacología , Líquenes/química , Animales , Larva/efectos de los fármacos , Dosificación Letal Mediana , Estructura Molecular , Análisis de Supervivencia
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