Asunto(s)
Neoplasias de los Párpados/patología , Linfoma de Células T/patología , Biopsia , Sondas de ADN/química , ADN de Neoplasias/análisis , Neoplasias de los Párpados/genética , Neoplasias de los Párpados/inmunología , Resultado Fatal , Reordenamiento Génico de Linfocito T , Humanos , Inmunohistoquímica , Linfoma de Células T/genética , Linfoma de Células T/inmunología , Masculino , Persona de Mediana Edad , Receptores de Antígenos de Linfocitos T alfa-beta/genética , Linfocitos T/inmunologíaRESUMEN
This report describes a case of focal myositis in a patient with mixed connective tissue disease. The patient presented with diffuse neck swelling and pseudothrombophlebitis of the left internal jugular vein. Other clinical features included a high fever, elevated erythrocyte sedimentation rate, and prompt improvement after administration of high-dose intravenous corticosteroid therapy. Criteria for polymyositis were absent, serum levels of creatine kinase remained normal, and there was no sign of recurrence during 3 years of followup. Results of immunoprecipitation for anti-Jo-1 and other myositis-specific autoantibodies remained negative in serial serum samples obtained before, during, and after the episode.
Asunto(s)
Edema/etiología , Venas Yugulares , Enfermedad Mixta del Tejido Conjuntivo/complicaciones , Miositis/etiología , Músculos del Cuello , Trombosis/etiología , Adulto , Femenino , HumanosRESUMEN
We describe a case of lambda light chain deposition disease (LCDD) which presented with symmetric, seronegative, nonerosive arthritis associated with skin nodules and widespread, progressive soft tissue induration. Multiple biopsies disclosed Congo red nonbirefringent deposits which stained strongly with lambda light chain antiserum, allowing distinction from amyloid arthropathy. This is the first report of musculoskeletal involvement in LCDD.