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1.
Int Anesthesiol Clin ; 62(4): 91-100, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233575

RESUMEN

ABSTRACT: Supraglottic airways have been utilized as an alternative to facemask ventilation and endotracheal intubation and thus have been essential to airway management since their introduction in the late 1980s. This chapter describes basic considerations in their use and an update on current clinical practice, with an emphasis on safe management. The devices have evolved to meet today's clinical airway challenges, and they provide benefits for patients and practitioners.


Asunto(s)
Manejo de la Vía Aérea , Intubación Intratraqueal , Máscaras Laríngeas , Humanos , Manejo de la Vía Aérea/métodos , Manejo de la Vía Aérea/instrumentación , Intubación Intratraqueal/métodos , Intubación Intratraqueal/instrumentación
2.
Cureus ; 15(7): e41617, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37565098

RESUMEN

Potentially difficult airways warrant the use of airway adjuncts, which, if not used with caution, can cause trauma to the oral cavity. Although most operators are familiar with modern airway adjuncts, as they are not routinely used, adverse events can occur. Since its introduction, a video laryngoscope (VL) has been lauded as a necessary instrument for airway management in and out of the operating room. This case report highlights right tonsillar tissue perforation with a GlideScope® VL (Verathon Incorporated, Bothell, Washington, USA), requiring primary closure by an otolaryngologist.

3.
Pak J Pharm Sci ; 34(6(Supplementary)): 2371-2377, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35039276

RESUMEN

To evaluate the anti-diabetic potential of aqueous methanolic extract of Conyza bonariensis amongst the Wistar rats. Phytochemical and High Performance Liquid Chromatography (HPLC) analyses of phenols and flavonoids were examined. The plant extract (250 and 500mg/kg/day) was explored for its anti-hyperglycemic effect for 14 days in normoglycemic and alloxan-induced diabetic rats using the oral glucose tolerance test (OGTT). HPLC analyses demonstrated the composition of the plant extract as gallic acid, cinnamic acid, quercetin, p-coumaric acid and syringic acid. The blood glucose concentrations in experimental diabetic as well as non-diabetic rats significantly decreased with doses 250 and 500 mg/kg in OGTT. Moreover, the significant drop in fasting glucose level was observed following 14 days of therapy. It also ameliorated the serum cholesterol, total protein, low and high density lipoproteins, glycosylated hemoglobin A1C and serum amylase with respect to untreated rats suffering from diabetes. There appeared to be no significant alteration with regard to body weight amongst the treated rats. The plant extract revamped the pancreatic islets of Langerhans and abridged alloxan-induced degenerative changes in the liver. It can be concluded that Conyza bonariensis extract has a pronounced hypoglycemic effect on diabetes due to the presence of phytochemicals.


Asunto(s)
Glucemia/efectos de los fármacos , Diabetes Mellitus Experimental/tratamiento farmacológico , Hipoglucemiantes/farmacología , Fitoquímicos/farmacología , Extractos Vegetales/farmacología , Aloxano , Animales , Biomarcadores/sangre , Glucemia/metabolismo , Conyza/química , Diabetes Mellitus Experimental/sangre , Diabetes Mellitus Experimental/inducido químicamente , Diabetes Mellitus Experimental/patología , Femenino , Hemoglobina Glucada/metabolismo , Hipoglucemiantes/aislamiento & purificación , Islotes Pancreáticos/efectos de los fármacos , Islotes Pancreáticos/metabolismo , Islotes Pancreáticos/patología , Lípidos/sangre , Hígado/efectos de los fármacos , Hígado/metabolismo , Hígado/patología , Masculino , Fitoquímicos/aislamiento & purificación , Extractos Vegetales/aislamiento & purificación , Ratas Wistar
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