RESUMEN
A study was made of the antioxidative activity (AOA), of the activity of glytathionreductase and catalase, and of SH-group concentration in suspensions of intact cells from eight fractions of the rat ascitic ovary tumor. A correlative bond was detected between AOA, the activity of antioxidative enzymes, and SH-group concentration. It was shown that antioxidative properties of the fractions containing resting (G0) and polyploid cells were higher than those of proliferating diploid cells.
Asunto(s)
Antioxidantes , Neoplasias Ováricas/metabolismo , Animales , Catalasa/análisis , Catalasa/metabolismo , Fraccionamiento Celular , ADN de Neoplasias/análisis , ADN de Neoplasias/biosíntesis , Femenino , Glutatión Reductasa/análisis , Glutatión Reductasa/metabolismo , Trasplante de Neoplasias , Neoplasias Ováricas/química , Poliploidía , Ratas , Compuestos de Sulfhidrilo/análisis , Compuestos de Sulfhidrilo/metabolismoRESUMEN
Injection of alpha-tocopherol acetate to albino mongrel rats potentiates antioxidant activity (AOA) that involves water-soluble factors of the antioxidant system in erythrocyte membranes. The activation of AOA by alpha-tocopherol takes place immediately after irradiation and drug injection and persists during the first 24 h following irradiation.
Asunto(s)
Antioxidantes , Membrana Eritrocítica/fisiología , Traumatismos Experimentales por Radiación/metabolismo , Vitamina E/análogos & derivados , alfa-Tocoferol/análogos & derivados , Animales , Inyecciones Intraperitoneales , Masculino , Oxidación-Reducción , Ratas , Estimulación Química , Tocoferoles , Vitamina E/administración & dosificaciónRESUMEN
The effect of tocopherol on the level of free fatty acids was quantitatively estimated at early times after irradiation. Tocopherol was shown to retard the growth of the free fatty acid level in rat erythrocyte membranes during the first 24 h following irradiation.