RESUMEN
In the world of evidence-based medicine, systematic reviews have long been the gold standard. But they have had a problem-they take forever. That is where ChatGPT-4 and automation come in. They are like a breath of fresh air, speeding things up and making the process more reliable. ChatGPT-4 is like having a super-smart assistant who can quickly assess bias risk in research studies. It is a game-changer, especially in a field where getting the latest research quickly can mean life or death for patients. Sure, it is not perfect, and we still need humans to keep an eye on things and ensure everything's ethical. But the future looks bright. With ChatGPT-4 and automation, evidence-based medicine is on the fast track to success.
RESUMEN
This case report presents a detailed exploration of an adult-onset 22q11 deletion syndrome, a rare genetic disorder typically diagnosed in children. The report highlights the diagnostic challenges posed by this atypical presentation, emphasizing the need for clinicians to consider such conditions in differential diagnoses, especially in adults. This case is remarkable for its late onset and mild symptoms, which significantly deviated from the common pediatric presentation, including hypocalcemia due to hypoparathyroidism and a fenestrated atrial septal defect without significant hemodynamic implications. The importance of recognizing the broad phenotypic variability of the syndrome and the implications for clinical practice are discussed, providing insights into the genetic and phenotypic diversity of the condition. In conclusion, this case illuminates the diverse clinical spectrum of adult-onset 22q11 deletion syndrome, emphasizing its relevance to clinical practice.