RESUMEN

Differences in virologic response were compared in 32 HIV-infected children with a nelfinavir trough concentration either below (n=7) or above (n=25) 0.8 mg/L. Virologic response at week 48 was observed in 29% of children with subtherapeutic nelfinavir troughs versus 80% in children with therapeutic nelfinavir troughs (P=.02).

Asunto(s)

Infecciones por VIH/sangre , Inhibidores de la Proteasa del VIH/farmacocinética , Nelfinavir/farmacocinética , Niño , Preescolar , Esquema de Medicación , Femenino , Infecciones por VIH/tratamiento farmacológico , Inhibidores de la Proteasa del VIH/sangre , Inhibidores de la Proteasa del VIH/uso terapéutico , Humanos , Masculino , Nelfinavir/sangre , Nelfinavir/uso terapéutico