RESUMEN
Triclosan (TCS) is an antimicrobial and antimycotic agent widely used in personal care products. In aquatic environments, both TCS and its biomethylated more persistent form, methyl-triclosan (MeTCS), are usually detected in wastewater effluents and rivers, where are commonly adsorbed to suspended solids and sediments. The aim of this study was to evaluate biochemical and physiological effects in Danio rerio after a short term (2 days) and prolonged (21 days) exposures to sediment spiked with TCS acting as the source of the pollutant in the assay. The activities of catalase (CAT), glutathione-s transferase (GST) and superoxide dismutase (SOD), lipid peroxidation levels (LPO), total capacity against peroxyl radicals (ACAP), and acetylcholinesterase enzymatic activity (AChE) were measured in liver, gills, and brain. Most of TCS on the spiked sediment was biotransformed to MeTCS and promoted different adverse effects on D. rerio. Gills were the most sensitive organ after 2 day-exposure, showing lipid damage and increased SOD activity. After 21 days of exposure, liver was the most sensitive organ, showing lower ACAP, increased LPO levels, and SOD and CAT activities. This is the first study reporting the effects on biochemical markers in D. rerio from a MeTCS sink resulting from sediment spiked with TCS.
Asunto(s)
Triclosán , Contaminantes Químicos del Agua , Acetilcolinesterasa , Animales , Catalasa/metabolismo , Estrés Oxidativo , Superóxido Dismutasa/metabolismo , Triclosán/toxicidad , Contaminantes Químicos del Agua/toxicidad , Pez Cebra/metabolismoRESUMEN
Describe una técnica para realizar bioensayos de toxicidad con peces de la ictiofauna bonaerense como organismo prueba; dicho método se aplicó para evaluar la calidad del agua del río Reconquista y el impacto producido por pulsos simulados de contaminación por vertido de un metal pesado (Cadmio)