RESUMEN
All 899 roommates exposed to methicillin-resistant Staphylococcus aureus (MRSA) index cases were studied over 57 months. MRSA detection is better at approximately 3 days (50%-55%) or 7 days (56%) after contact has been broken than day 0 (30%). Polymerase chain reaction testing at day 3 performs similarly to culture at day 7. Nasal/rectal screening provides superior detection than nasal alone. Those exposed >48 hours are at significantly greater risk of colonization.
Asunto(s)
Staphylococcus aureus Resistente a Meticilina/aislamiento & purificación , Habitaciones de Pacientes , Infecciones Estafilocócicas/epidemiología , Infecciones Estafilocócicas/transmisión , Técnicas Bacteriológicas/métodos , Humanos , Control de Infecciones/métodos , Tamizaje Masivo/métodos , Mucosa Nasal/microbiología , Reacción en Cadena de la Polimerasa/métodos , Recto/microbiología , Infecciones Estafilocócicas/microbiología , Factores de TiempoRESUMEN
All medical and high-risk surgical patients were screened for methicillin-resistant Staphylococcus aureus colonization over 3.5 years. The sensitivities of nasal and rectal swabs were 68% and 62%, respectively. Naris and open-skin-site swabs detected 467 (74%) of 627 adult carriers identified. Rectal swabs detected an additional 160 (26%) carriers.
Asunto(s)
Staphylococcus aureus Resistente a Meticilina , Mucosa Nasal/microbiología , Recto/microbiología , Infecciones Estafilocócicas/diagnóstico , Adulto , Portador Sano/microbiología , Infección Hospitalaria/microbiología , Humanos , Vigilancia de la Población , Sensibilidad y EspecificidadRESUMEN
An updated IDI-MRSA assay version was released to address the assay's low positive predictive value (PPV). A prospective analysis of two assay versions indicated no significant improvement in the PPV. Colonization by methicillin-resistant Staphylococcus aureus in 24% of patients would not have been detected if only nasal samples had been tested, as approved, by this molecular method.