RESUMEN
The cytomorphological and biochemical composition of the blood has been studied for the deep-dwelling (bottom) morphotype of the Baikal omul infected by plerocercoids of Diphyllobothrium dendriticum, during the fish spawning migration. A decrease in hemoglobin synthesis and an increase in the proliferative activity of erythroid cells have been registered. The changes in the leukocyte population composition, immunoglobulin, and total protein concentrations evidenced a disorder of blood cell proliferation and differentiation and suppression of the immune response in the infected fish. The changes in the humoral and cell factors of homeostasis in Coregonus migratorius infected by D. dendriticum during the spawning period remain within the limits of the adaptive possibilities of the species.
Asunto(s)
Difilobotriosis/veterinaria , Diphyllobothrium/patogenicidad , Enfermedades de los Peces/sangre , Enfermedades de los Peces/parasitología , Salmonidae/parasitología , Animales , Difilobotriosis/sangre , Difilobotriosis/inmunología , Enfermedades de los Peces/inmunología , Proteínas de Peces/sangre , Inmunidad Humoral , Inmunoglobulinas/sangre , Leucocitos/patología , SiberiaRESUMEN
Morphofunctional changes induced by the tapeworm in the thymus and blood of its definitive host, by an example of the experimental model "Diphyllobothrium dendriticum--Mesocricetus auratus", have been investigated. The morphofunctional changes in the thymus and immunological transformations in the organism of infested hamster are evidences of rather high immunogenic effect of the D. dendriticum antigens on the definitive host at the period of active growth of the parasites.
Asunto(s)
Difilobotriosis/veterinaria , Diphyllobothrium/crecimiento & desarrollo , Enfermedades de los Roedores/inmunología , Enfermedades de los Roedores/parasitología , Linfocitos T/inmunología , Timo/inmunología , Animales , Cricetinae , Difilobotriosis/inmunología , Difilobotriosis/parasitología , Femenino , Recuento de Linfocitos , Masculino , MesocricetusRESUMEN
The morphological structure of the blood in herring gull nestlings and their immune system response to experimental infection with tapeworm Diphyllobothrium dendriticum have been studied. The leukocyte reaction pattern and the dynamics of immunoglobulin synthesis and populations of immunocompetent cells in the blood of nestlings during early invasion indicated a short duration of the cellular immune response and an insignificant humoral immune response. A pronounced trend to decrease in the hemoglobin level in the blood of infected nestlings has been revealed and this reduction was in part compensated by intensified erythropoiesis. It is shown, that the changes in hematologic and immune responses of the obligate definitive host provide for the mutual host-parasite adaptation.